# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4375439 | B | Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exchange preincubated for 10 mins followed by NaI-substituted PBS addition and measured by YFP-based fluorescence assay | Mus musculus | 45 | cell-based format | Scientific Literature | ||
2. | ALA4375440 | B | Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/bicarbonate exchange by measuring decrease in cytoplasmic alkalinization by BCECF probe-based fluorescence assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
3. | ALA4418163 | B | Inhibition of myc-tagged mouse Slc26a3 expressed in COS7 co-expressing EYFP-HIF assessed as effect on SCN(-) gradient at 25 uM by YFP-based fluorescence quenching assay | Mus musculus | 1 | assay format | Patent Bioactivity Data | ||
4. | ALA5053125 | B | Inhibition of mouse Slc26a3 transfected in rat FRT cells preincubated with forskolin, 8-Br-cGMP and PMA and measured by fluorescence assay | Mus musculus | 51 | cell-based format | Patent Bioactivity Data | ||
5. | ALA5053126 | B | Inhibition of mouse Slc26a3 transfected in rat FRT cells at 10 uM preincubated with forskolin, 8-Br-cGMP and PMA and measured by fluorescence assay relative to control | Mus musculus | 1 | cell-based format | Patent Bioactivity Data |