# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1054909 | Functional | Agonist activity at dog recombinant adrenergic beta3 receptor expressed in CHO cells assessed as stimulation of cAMP level after 1 hr by enzyme immunoassay | Canis lupus familiaris | 1 | ALA1153472 | cell-based format | Scientific Literature | |
2. | ALA1007108 | Functional | Agonist activity at dog recombinant beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immunoassay | Canis lupus familiaris | 17 | ALA1138480 | cell-based format | Scientific Literature | |
3. | ALA1021863 | Functional | Agonist activity at dog recombinant beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immuno assay | Canis lupus familiaris | 8 | ALA1157533 | cell-based format | Scientific Literature | |
4. | ALA1021865 | Functional | Intrinsic activity at dog recombinant beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immuno assay relative to isoproterenol | Canis lupus familiaris | 8 | ALA1157533 | cell-based format | Scientific Literature | |
5. | ALA981736 | Functional | Agonist activity at dog cloned adrenergic beta3 receptor expressed in CHO cells assessed as cAMP accumulation | Canis lupus familiaris | 3 | ALA1144172 | cell-based format | Scientific Literature | |
6. | ALA982603 | Functional | Agonist activity at dog cloned adrenergic beta3 receptor assessed as inhibition of carbachol-induced increase in intravesical pressure at 10 ug/kg, iv | Canis lupus familiaris | 1 | ALA1144172 | assay format | Scientific Literature | |
7. | ALA982604 | Functional | Agonist activity at dog cloned adrenergic beta3 receptor assessed as inhibition of carbachol-induced increase in intravesical pressure at 32 ug/kg, iv | Canis lupus familiaris | 2 | ALA1144172 | assay format | Scientific Literature | |
8. | ALA977254 | Functional | Agonist activity at dog beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation | Canis lupus familiaris | 3 | ALA1155947 | cell-based format | Scientific Literature | |
9. | ALA952046 | Functional | Agonist activity at dog beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation | Canis lupus familiaris | 3 | ALA1142325 | cell-based format | Scientific Literature | |
10. | ALA952048 | Binding | Intrinsic activity at dog beta3 adrenergic receptor expressed in CHO cells assessed as ratio between maximal effect of drug to maximal effect of isoproterenol | Canis lupus familiaris | 3 | ALA1142325 | cell-based format | Scientific Literature | |
11. | ALA3128844 | Functional | Agonist activity at dog beta-3 adrenergic receptor expressed in CHO cells assessed as increase in intracellular cAMP accumulation at 10'-10 to 10'-5 M after 30 mins by time-resolved fluorescence assay relative to R-(-)isoproterenol | Canis lupus familiaris | 3 | ALA3124772 | cell-based format | Scientific Literature | |
12. | ALA3128845 | Functional | Agonist activity at dog beta-3 adrenergic receptor expressed in CHO cells assessed as increase in intracellular cAMP accumulation after 30 mins by time-resolved fluorescence assay | Canis lupus familiaris | 3 | ALA3124772 | cell-based format | Scientific Literature | |
13. | ALA3766299 | Functional | Agonist activity at dog beta3 adrenergic receptor expressed in CHO cells assessed as accumulation of cAMP after 30 mins by TR-FRET assay | Canis lupus familiaris | 4 | ALA3763146 | cell-based format | Scientific Literature |