# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4351511 | B | Displacement of [3H]-flumazenil from human GABAA alpha5beta2gamma2 receptor expressed in HEK293 cell membranes measured after 2 hrs by liquid scintillation counting method | Homo sapiens | 2 | ALA4350959 | cell-based format | Scientific Literature | |
2. | ALA4398035 | B | Agonist activity at recombinant human GABA-A alpha5beta2gamma2S receptor transiently expressed in human tsA201 cells incubated for 30 mins and measured up to 90 secs by FMP dye based FLIPR membrane potential blue assay | Homo sapiens | 16 | ALA4396887 | cell-based format | Scientific Literature | |
3. | ALA4398036 | B | Agonist activity at recombinant human GABA-A alpha5beta2gamma2S receptor transiently expressed in human tsA201 cells assessed as GABA-induced maximum response incubated for 30 mins and measured up to 90 secs by FMP dye based FLIPR membrane potential blue assay relative to GABA | Homo sapiens | 15 | ALA4396887 | cell-based format | Scientific Literature | |
4. | ALA4716916 | B | Allosteric modulation of GABAA alpha5beta2gamma2 (unknown origin) expressed in Xenopus oocytes assessed as potentiation of GABA-induced current response at 3 uM at -80 mV holding potential incubated for 3 mins by two electrode voltage clamp method | Homo sapiens | 1 | ALA4715701 | cell-based format | Scientific Literature | |
5. | ALA5098940 | B | Antagonist activity at human alpha5beta2gamma2 GABAA receptor expressed in HEK293 cells by FMP assay | Homo sapiens | 2 | ALA5096209 | cell-based format | Scientific Literature | |
6. | ALA5098947 | B | Antagonist activity at human alpha5beta2gamma2 GABAA receptor expressed in HEK cells by FMP assay | Homo sapiens | 2 | ALA5096209 | cell-based format | Scientific Literature | |
7. | ALA5146043 | B | Displacement of [3H]flunitrazepam from human recombinant alpha5beta2gamma2 GABAA receptor expressed in HEK cell membrane by competitive radioligand binding assay | Homo sapiens | 21 | ALA5143601 | cell membrane format | Scientific Literature |