| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4419699 | B | Binding affinity to human LARG (765 to 1138 residues) DH-PH module expressed in mouse NIH/3T3 cells assessed as reduction in LARG binding to human full length RhoA (1 to 193 residues) by measuring relative LARG binding level at 15 uM in presence of 15 uM Rhosin/G04 pull-down assay (Rvb = 1 No unit) | Homo sapiens | 1 | ALA4419173 | cell-based format | Patent Bioactivity Data | |
| 2. | ALA4419700 | B | Binding affinity to human LARG (765 to 1138 residues) DH-PH module expressed in mouse NIH/3T3 cells assessed as reduction in LARG binding to human full length RhoA (1 to 193 residues) by measuring relative LARG binding level at 5 uM in presence of 5 uM Rhosin/G04 pull-down assay (Rvb = 1 No unit) | Homo sapiens | 1 | ALA4419173 | cell-based format | Patent Bioactivity Data | |
| 3. | ALA4419701 | B | Binding affinity to human LARG (765 to 1138 residues) DH-PH module expressed in mouse NIH/3T3 cells assessed as reduction in LARG binding to human full length RhoA (1 to 193 residues) by measuring relative LARG binding level at 2.5 uM in presence of 2.5 uM Rhosin/G04 pull-down assay (Rvb = 1 No unit) | Homo sapiens | 1 | ALA4419173 | cell-based format | Patent Bioactivity Data | |
| 4. | ALA4419702 | B | Binding affinity to human LARG (765 to 1138 residues) DH-PH module expressed in mouse NIH/3T3 cells assessed as reduction in LARG binding to human full length RhoA (1 to 193 residues) by measuring relative LARG binding level at 50 uM pull-down assay (Rvb = 1 No unit) | Homo sapiens | 2 | ALA4419173 | cell-based format | Patent Bioactivity Data | |
| 5. | ALA4419703 | B | Binding affinity to human LARG (765 to 1138 residues) DH-PH module expressed in mouse NIH/3T3 cells assessed as reduction in LARG binding to human full length RhoA (1 to 193 residues) by measuring relative LARG binding level at 30 uM pull-down assay (Rvb = 1 No unit) | Homo sapiens | 2 | ALA4419173 | cell-based format | Patent Bioactivity Data | |
| 6. | ALA4419704 | B | Binding affinity to human LARG (765 to 1138 residues) DH-PH module expressed in mouse NIH/3T3 cells assessed as reduction in LARG binding to human full length RhoA (1 to 193 residues) by measuring relative LARG binding level at 10 uM pull-down assay (Rvb = 1 No unit) | Homo sapiens | 2 | ALA4419173 | cell-based format | Patent Bioactivity Data | |
| 7. | ALA4419705 | B | Binding affinity to human LARG (765 to 1138 residues) DH-PH module expressed in mouse NIH/3T3 cells assessed as reduction in LARG binding to human full length RhoA (1 to 193 residues) by measuring relative LARG binding level at 5 uM pull-down assay (Rvb = 1 No unit) | Homo sapiens | 2 | ALA4419173 | cell-based format | Patent Bioactivity Data | |
| 8. | ALA4419740 | B | Inhibition of GFP-tagged human p115 RhoGEF DH-PH module expressed in mouse NIH/3T3 cells assessed as reduction in human full length RhoA (1 to 193 residues) interaction with p115 RhoGEF at 30 to 50 uM incubated for 1 hr by Western blot analysis based GST-RhoA pull-down assay | Homo sapiens | 1 | ALA4419173 | cell-based format | Patent Bioactivity Data |
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