# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4377049 | B | Antagonist activity at TRPC4/TRPC1 in human A498 cells assessed as reduction in englerin A-induced calcium entry preincubated for 30 mins followed by englerin A addition by fluorescence method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
2. | ALA4377066 | B | Inhibition of human TRPC4/human TRPC1 expressed in HEK293 cells assessed as reduction in englerin A-induced calcium entry incubated for 30 mins by Fluo-4AM dye based fluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA4622714 | A | Agonist activity at human TRPC4/TRPC1 expressed in HEK293 Tet cells assessed as increase in intracellular calcium level at 1 uM measured at 5 secs interval for 300 secs by Fura-2AM dye based fluorescence assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
4. | ALA4622715 | A | Agonist activity at human TRPC4/TRPC1 expressed in HEK293 Tet cells assessed as increase in intracellular calcium level at 0.1 uM measured at 5 secs interval for 300 secs by Fura-2AM dye based fluorescence assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
5. | ALA4622716 | A | Agonist activity at human TRPC4/TRPC1 expressed in HEK293 Tet cells assessed as increase in intracellular calcium level at 1 uM measured at 5 secs interval for 300 secs in presence of TRPC4/5 antagonist Pico145 by Fura-2AM dye based fluorescence assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
6. | ALA4622723 | A | Potency index, ratio of test compound to englerin A for agonist activity at human TRPC4/TRPC1 expressed in HEK293 Tet cells | Homo sapiens | 3 | cell-based format | Scientific Literature |