# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4357425 | Binding | Inhibition of BK alpha/beta-4 in PTZ-stimulated rat hippocampal pyramidal neurons assessed as longer interval of interspike at -80mV holding potential measured after 10 mins during 300pA current injection by whole cell current clamp assay | Rattus norvegicus | 1 | ALA4354835 | protein complex format | Scientific Literature | |
2. | ALA4357426 | Binding | Inhibition of BK alpha/beta-4 in rat hippocampal pyramidal neurons assessed as inhibition of PTZ-induced action potential at -80 mV holding potential at 300 pA current injection measured after 10 mins by whole cell current clamp assay | Rattus norvegicus | 1 | ALA4354835 | assay format | Scientific Literature | |
3. | ALA4357427 | Binding | Inhibition of BK alpha/beta-4 in PTZ-stimulated rat hippocampal pyramidal neurons assessed as appearance of more action potential failures at -80mV holding potential measured after 10 mins during 300pA current injection by whole cell current clamp assay | Rattus norvegicus | 1 | ALA4354835 | protein complex format | Scientific Literature | |
4. | ALA4357428 | Binding | Inhibition of BK alpha/beta-4 in PTZ-stimulatedrat hippocampal pyramidal neurons assessed as reduction in neuronal firing rate at -80mV holding potential in presence of 200 to 300 pA current injection measured after 10 mins by whole cell current clamp assay | Rattus norvegicus | 1 | ALA4354835 | protein complex format | Scientific Literature | |
5. | ALA4357429 | Binding | Inhibition of BK alpha/beta-4 in PTZ-stimulated rat hippocampal pyramidal neurons assessed as larger action potential width at 300 pA current injection at -80mV holding potential measured after 10 mins by whole cell current clamp assay | Rattus norvegicus | 3 | ALA4354835 | protein complex format | Scientific Literature | |
6. | ALA4357430 | Binding | Inhibition of BK alpha/beta-4 in PTZ-stimulated rat hippocampal pyramidal neurons assessed as slower decay of after hyperpolarization at 300 pA at -80mV holding potential measured after 10 mins by whole cell current clamp assay | Rattus norvegicus | 3 | ALA4354835 | protein complex format | Scientific Literature | |
7. | ALA4357431 | Binding | Inhibition of BK alpha/beta-4 in PTZ-stimulated rat hippocampal pyramidal neurons assessed as increase in AHP size at 300 pA at -80mV holding potential measured after 10 mins by whole cell current clamp assay | Rattus norvegicus | 3 | ALA4354835 | protein complex format | Scientific Literature |