#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA5249941	B	Protac activity at CRBN/EGFR Del19/T790M/C797S mutant (unknown origin) expressed in mouse BaF3 cells assessed as degradation of EGFR Del19/T790M/C797S mutant incubated for 24 hrs by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
2.	ALA5249942	B	Protac activity at CRBN/EGFR L858R/T790M/C797S mutant (unknown origin) expressed in mouse BaF3 cells assessed as degradation of EGFR L858R/T790M/C797S incubated for 24 hrs by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
3.	ALA4313025	A	Induction of CRBN-mediated EGFR degradation in human U251 cells at 500 nM after 4 hrs by immunoblot analysis	Homo sapiens	1		cell-based format	Scientific Literature
4.	ALA4380724	B	Protac activity at CRBN/EGFR exon 19 deletion mutant in human HCC827 cells assessed as induction of EGFR degradation at up to 1 uM treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis	Homo sapiens	4		cell-based format	Scientific Literature
5.	ALA4380728	B	Protac activity at CRBN/EGFR exon 19 deletion mutant in human HCC827 cells assessed as induction of EGFR degradation treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
6.	ALA4380730	B	Protac activity at CRBN/EGFR L858R mutant in human H3255 cells assessed as induction of EGFR degradation treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
7.	ALA4380732	B	Protac activity at CRBN/EGFR exon 19 deletion mutant in human HCC827 cells assessed as induction of EGFR degradation at >=50 nM treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis relative to control	Homo sapiens	1		cell-based format	Scientific Literature
8.	ALA4380734	B	Protac activity at CRBN/EGFR L858R mutant in human H3255 cells assessed as induction of EGFR degradation at >=50 nM treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis relative to control	Homo sapiens	1		cell-based format	Scientific Literature
9.	ALA4380736	B	Protac activity at CRBN/EGFR exon 19 deletion mutant in human HCC827 cells assessed as induction of EGFR degradation at 10 uM treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis relative to control	Homo sapiens	1		cell-based format	Scientific Literature
10.	ALA4380738	B	Protac activity at CRBN/EGFR L858R mutant in human H3255 cells assessed as induction of EGFR degradation at 10 uM treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
11.	ALA4380749	B	Protac activity at CRBN/EGFR exon 19 deletion mutant in human HCC827 cells assessed as reduction in EGFR autophosphorylation up to 10 uM treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
12.	ALA4380750	B	Protac activity at CRBN/EGFR L858R mutant in human H3255 cells assessed as reduction in EGFR autophosphorylation up to 10 uM treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
13.	ALA4380751	B	Protac activity at CRBN/EGFR exon 19 deletion mutant in human HCC827 cells assessed as reduction in AKT phosphorylation up to 10 uM treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
14.	ALA4380752	B	Protac activity at CRBN/EGFR L858R mutant in human H3255 cells assessed as reduction in AKT phosphorylation up to 10 uM treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
15.	ALA4380770	B	Protac activity at CRBN/EGFR exon 19 deletion mutant in human HCC827 cells assessed as time required to induce 50% EGFR degradation at 100 nM treated 8 hrs post serum starvation by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
16.	ALA4380771	B	Protac activity at CRBN/EGFR exon 19 deletion mutant in human HCC827 cells assessed as induction of EGFR degradation at 100 nM treated 8 hrs post serum starvation measured after 12 hrs by Western blot analysis relative to control	Homo sapiens	1		cell-based format	Scientific Literature
17.	ALA4380774	B	Protac activity at CRBN/EGFR L858R mutant in human H3255 cells assessed as induction of EGFR degradation at 100 nM treated 8 hrs post serum starvation by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
18.	ALA4380775	B	Protac activity at CRBN/EGFR L858R mutant in human H3255 cells assessed as reduction in AKT phosphorylation at 100 nM treated 8 hrs post serum starvation by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
19.	ALA4380778	B	Protac activity at CRBN/EGFR exon 19 deletion mutant in human HCC827 cells assessed as induction of EGFR degradation at 0.1 to 1 uM incubated for 8 hrs in absence of FBS by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
20.	ALA4380779	B	Protac activity at CRBN/EGFR L858R mutant in human H3255 cells assessed as induction of EGFR degradation at 0.1 to 1 uM incubated for 8 hrs in absence of FBS by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature