| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4313018 | A | Induction of CRBN-mediated CDK1 degradation in human U251 cells at 500 nM after 4 hrs by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA4819962 | B | PROTAC activity at CRBN/CDK1 in human MV4-11 cells assessed as induction of CDK1 degradation at 31.25 to 500 nM measured after 3 hrs by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4822293 | B | Protac activity at CDK1/CRBN in human HEK293 cells assessed as degradation of CDK1 at 0.01 to 10 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4822302 | B | Protac activity at CDK1/CRBN in human HEK293 cells assessed as degradation of CDK1 at 1 uM measured upto 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4822315 | B | Protac activity at CDK1/CRBN in human HEK293 cells assessed as degradation of CDK1 at 1 uM incubated for 24 hrs in presence of MG132 by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4831159 | B | Protac activity at CRBN/CDK1 in human MDA-MB-231 cells assessed as induction of degradation of CDK1 at 0.01 to 2.5 uM incubated for 4 to 8 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4831172 | B | Protac activity at CRBN/CDK1 in human MDA-MB-231 cells assessed as induction of degradation of CDK1 at 100 to 500 nM incubated for 4 to 8 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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