# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4322324 | B | Induction of CRBN-mediated Bcl-2 degradation in human HeLa cells assessed as relative abundance at 10 uM after 12 hrs by Western blot analysis (Rvb = 1 No_unit) | Homo sapiens | 14 | ALA4321796 | cell-based format | Scientific Literature | |
2. | ALA4322325 | B | Induction of CRBN-mediated Bcl-2 degradation in human HeLa cells assessed as relative abundance at 1 uM after 12 hrs by Western blot analysis (Rvb = 1 No_unit) | Homo sapiens | 12 | ALA4321796 | cell-based format | Scientific Literature | |
3. | ALA4322327 | B | Induction of CRBN-mediated Bcl-2 degradation in human HeLa cells at 10 uM after 12 hrs by Western blot analysis relative to control | Homo sapiens | 7 | ALA4321796 | cell-based format | Scientific Literature | |
4. | ALA4322329 | B | Induction of CRBN-mediated Bcl-2 degradation in human HeLa cells after 12 hrs by Western blot analysis | Homo sapiens | 1 | ALA4321796 | cell-based format | Scientific Literature | |
5. | ALA4322333 | B | Induction of CRBN-mediated Bcl-2 degradation in human HeLa cells assessed as reduction in Bcl-2 level at 1 uM after 12 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA4321796 | cell-based format | Scientific Literature | |
6. | ALA4322334 | B | Induction of CRBN-mediated Bcl-2 degradation in human HeLa cells assessed as reduction in Bcl-2 level at 10 uM after 12 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA4321796 | cell-based format | Scientific Literature | |
7. | ALA4322335 | B | Induction of CRBN-mediated Bcl-2 degradation in human HeLa cells assessed as relative abundance at 3 uM after 12 hrs by Western blot analysis (Rvb = 1 No_unit) | Homo sapiens | 3 | ALA4321796 | cell-based format | Scientific Literature | |
8. | ALA4322336 | B | Induction of CRBN-mediated Bcl-2 degradation in human HeLa cells assessed as relative abundance at 0.3 uM after 12 hrs by Western blot analysis (Rvb = 1 No_unit) | Homo sapiens | 3 | ALA4321796 | cell-based format | Scientific Literature | |
9. | ALA4322338 | B | Induction of CRBN-mediated Bcl-2 degradation in human HeLa cells assessed as relative abundance at 0.1 uM after 12 hrs by Western blot analysis (Rvb = 1 No_unit) | Homo sapiens | 3 | ALA4321796 | cell-based format | Scientific Literature | |
10. | ALA4322343 | B | Induction of CRBN-mediated Bcl-2 degradation in human HeLa cells at 10 uM by Western blot analysis | Homo sapiens | 1 | ALA4321796 | cell-based format | Scientific Literature | |
11. | ALA4322346 | B | Induction of CRBN-mediated Bcl-2 degradation in human HeLa cells assessed as relative abundance at 10 uM measured at 20 hrs by Western blot analysis (Rvb = 1 No_unit) | Homo sapiens | 3 | ALA4321796 | cell-based format | Scientific Literature | |
12. | ALA4322350 | B | Induction of CRBN-mediated Bcl-2 degradation in human HeLa cells assessed as relative abundance at 10 uM measured at 2 hrs by Western blot analysis (Rvb = 1 No_unit) | Homo sapiens | 3 | ALA4321796 | cell-based format | Scientific Literature | |
13. | ALA4322351 | B | Induction of CRBN-mediated Bcl-2 degradation in human HeLa cells assessed as relative abundance at 10 uM measured at 4 hrs by Western blot analysis (Rvb = 1 No_unit) | Homo sapiens | 3 | ALA4321796 | cell-based format | Scientific Literature | |
14. | ALA4322352 | B | Induction of CRBN-mediated Bcl-2 degradation in human HeLa cells assessed as relative abundance at 10 uM measured at 8 hrs by Western blot analysis (Rvb = 1 No_unit) | Homo sapiens | 3 | ALA4321796 | cell-based format | Scientific Literature | |
15. | ALA4322353 | B | Induction of CRBN-mediated Bcl-2 degradation in human HeLa cells assessed as relative abundance at 10 uM measured at 16 hrs by Western blot analysis (Rvb = 1 No_unit) | Homo sapiens | 3 | ALA4321796 | cell-based format | Scientific Literature | |
16. | ALA4322354 | B | Induction of CRBN-mediated Bcl-2 degradation in human HeLa cells assessed as relative abundance at 10 uM measured at 24 hrs by Western blot analysis (Rvb = 1 No_unit) | Homo sapiens | 3 | ALA4321796 | cell-based format | Scientific Literature | |
17. | ALA4322358 | B | Induction of CRBN-mediated Bcl-2 degradation in human HeLa cells measured at 12 hrs by Western blot analysis | Homo sapiens | 1 | ALA4321796 | cell-based format | Scientific Literature | |
18. | ALA4322362 | B | Induction of CRBN-mediated Bcl-2 degradation in human HeLa cells by Western blot analysis | Homo sapiens | 1 | ALA4321796 | cell-based format | Scientific Literature | |
19. | ALA4322366 | B | Induction of CRBN-mediated Bcl-2 degradation in human HeLa cells at 10 uM pretreated with proteasome inhibitor MG-132 followed by compound addition by Western blot analysis | Homo sapiens | 1 | ALA4321796 | cell-based format | Scientific Literature | |
20. | ALA4322367 | B | Induction of CRBN-mediated Bcl-2 degradation in human HeLa cells at 10 uM pretreated with Bcl-2 inhibitor Nap-1 followed by compound addition by Western blot analysis | Homo sapiens | 1 | ALA4321796 | cell-based format | Scientific Literature |