| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5249954 | B | Protac activity at CRBN/CDK4 in human MDA-MB-231 cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA4312979 | B | Induction of CRBN-mediated CDK4 degradation in human U251 cells after 24 hrs by immunoblot analysis | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 3. | ALA4312987 | B | Induction of CRBN-mediated CDK4 degradation in human U251 cells at 1 uM after 24 hrs by immunoblot analysis | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 4. | ALA4312999 | B | Induction of CRBN-mediated CDK4 degradation in human U251 cells assessed as CDK4 level at 0.1 nM after 24 hrs by immunoblot analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4313000 | B | Induction of CRBN-mediated CDK4 degradation in human U251 cells assessed as CDK4 level at 0.33 nM after 24 hrs by immunoblot analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4313001 | B | Induction of CRBN-mediated CDK4 degradation in human U251 cells assessed as CDK4 level at 1 nM after 24 hrs by immunoblot analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4313002 | B | Induction of CRBN-mediated CDK4 degradation in human U251 cells assessed as CDK4 level at 3.3 nM after 24 hrs by immunoblot analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4313003 | B | Induction of CRBN-mediated CDK4 degradation in human U251 cells assessed as CDK4 level at 10 nM after 24 hrs by immunoblot analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4313004 | B | Induction of CRBN-mediated CDK4 degradation in human U251 cells assessed as CDK4 level at 33 nM after 24 hrs by immunoblot analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4313005 | B | Induction of CRBN-mediated CDK4 degradation in human U251 cells assessed as CDK4 level at 100 nM after 24 hrs by immunoblot analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4313006 | B | Induction of CRBN-mediated CDK4 degradation in human U251 cells assessed as CDK4 level at 330 nM after 24 hrs by immunoblot analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4313007 | B | Induction of CRBN-mediated CDK4 degradation in human U251 cells assessed as CDK4 level at 1000 nM after 24 hrs by immunoblot analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4313008 | B | Induction of CRBN-mediated CDK4 degradation in human U251 cells assessed as CDK4 level at 3300 nM after 24 hrs by immunoblot analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4313009 | B | Induction of CRBN-mediated CDK4 degradation in human U251 cells assessed as CDK4 level at 10000 nM after 24 hrs by immunoblot analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4313020 | B | Induction of CRBN-mediated CDK4 degradation in human U251 cells at 500 nM after 4 hrs by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4313029 | B | Induction of CRBN-mediated CDK4 degradation in human U251 cells at 500 nM after 4 hrs by TMT Mass spectrometry based proteomic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4313033 | B | Protac activity at CRBN/FLAG-tagged human CDK4 expressed in human U251 cells at 500 nM after 28 hrs by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4313055 | B | Induction of CRBN-mediated CDK4 in palbociclib-resistant human MCF-7 cells with CDK6 gene amplification at 1 uM after 24 hrs by immunoblot analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 19. | ALA4313056 | B | Induction of CRBN-mediated CDK4 in palbociclib-resistant Fat1 knockout human MCF-7 cells with at 1 uM after 6 days by immunoblot analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 20. | ALA4341453 | B | Induction of CRBN-mediated CDK4 degradation in human MIAPaCa2 cells at 0.5 uM measured after 4 hrs by western blot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature |
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