| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4324545 | B | Protac activity against CRBN/MEK2 in human HT-29 cells harboring BRAF V600E variant assessed as degradation of MEK2 at 0.3 to 3 uM after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA4712220 | B | Protac activity at CRBN/MEK2 in human HT-29 cells assessed as induction of MEK1 degradation at 0.3 to 3 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 3. | ALA4712229 | B | Protac activity at CRBN/MEK2 in human HT-29 cells assessed as time for induction of MEK2 degradation at 0.3 uM by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4712231 | B | Protac activity at CRBN/MEK2 in human HT-29 cells assessed as time for maximum induction of MEK2 degradation at 0.3 uM by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4712233 | B | Protac activity at CRBN/MEK2 in human SK-MEL-28 cells assessed as induction of MEK2 degradation at 0.3 to 3 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4712240 | B | Protac activity at CRBN/MEK2 in human HT-29 cells assessed as induction of MEK2 degradation incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4712242 | B | Protac activity at CRBN/MEK2 in human SK-MEL-28 cells assessed as induction of MEK2 degradation incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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