| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4356733 | B | Protac activity at CRBN/STAT3 in human MOLM16 cells assessed as degradation of STAT3 incubated for 4 hrs by Western blot analysis | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
| 2. | ALA4356734 | B | Protac activity at CRBN/STAT3 in human MOLM16 cells assessed as degradation of STAT3 at 1 uM incubated for 4 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 3. | ALA4356735 | B | Protac activity at CRBN/STAT3 in human MOLM16 cells assessed as degradation of phosphorylated STAT3 Y705 at 1 uM incubated for 4 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA4356736 | B | Protac activity at CRBN/STAT3 in human MOLM16 cells assessed as degradation of STAT3 up to 10 uM incubated for 4 hrs by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA4356737 | B | Protac activity at CRBN/STAT3 in human MOLM16 cells assessed as degradation of phosphorylated STAT3 Y705 upto 10 uM incubated for 4 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA4356738 | B | Protac activity at CRBN/STAT3 in human SUDHL1 cells assessed as degradation of STAT3 upto 10 uM incubated for 16 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA4356739 | B | Protac activity at CRBN/STAT3 in human SUDHL1 cells assessed as degradation of phosphorylated STAT3 Y705 upto 10 uM incubated for 16 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA4356740 | B | Protac activity at CRBN/STAT3 in human SUDHL1 cells assessed as degradation of STAT3 upto 5 uM incubated for 16 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA4356741 | B | Protac activity at CRBN/STAT3 in human SUDHL1 cells assessed as degradation of phosphorylated STAT3 Y705 upto 5 uM incubated for 16 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA4356742 | B | Protac activity at CRBN/STAT3 in human SUDHL1 cells assessed as degradation of STAT3 incubated for 16 hrs by Western blot analysis | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
| 11. | ALA4356745 | B | Protac activity at CRBN/STAT3 in human MOLM16 cells assessed as degradation of STAT3 at 0.01 to 10 uM incubated for 4 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4356746 | B | Protac activity at CRBN/STAT3 in human MOLM16 cells assessed as degradation of STAT3 at 10 uM incubated for 4 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA4356759 | B | Protac activity at CRBN/STAT3 in human SUDHL1 cells assessed as degradation of STAT3 at 0.01 to 10 uM incubated for 18 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4356760 | B | Protac activity at CRBN/STAT3 in human SUDHL1 cells assessed as degradation of STAT3 at 10 uM incubated for 18 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 15. | ALA4713706 | B | Protac activity at CRBN/STAT3 in human OVCAR-3 cells assessed as depletion of STAT3 at 2 to 20 uM after 12 hrs by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4713707 | B | Protac activity at CRBN/STAT3 in human OVCAR-3 cells assessed as decrease in STAT3 phosphorylation at 2 to 20 uM after 6 hrs by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4713708 | B | Protac activity at CRBN/STAT3 in human OVCAR-3 cells assessed as decrease in STAT3 expression at 2 to 10 uM incubated for 24 hrs in presence of proteasome inhibitor MG132 by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4713709 | B | Protac activity at CRBN/STAT3 in human OVCAR-3 cells assessed as induction of STAT3 degradation at 1 to 20 uM incubated for 12 hrs in presence of competitive CRBN ligand pomalidomide by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4713711 | B | Protac activity at CRBN/STAT3 in human BxPC-3 cells assessed as decrease in STAT3 expression level after 12 hrs by western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 20. | ALA4713712 | B | Protac activity at CRBN/STAT3 in human BxPC-3 cells assessed as induction of STAT3 degradation at 1 to 5 uM after 12 hrs in presence of proteasome inhibitor bortezomib by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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