# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4341456 | B | Induction of CRBN-mediated CDK7 degradation in human MIAPaCa2 cells at 0.5 uM measured after 24 hrs by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
2. | ALA4819959 | B | PROTAC activity at CRBN/CDK7 in human MV4-11 cells assessed as induction of CDK7 degradation at 31.25 to 500 nM measured after 3 hrs by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA4822288 | B | Protac activity at CDK7/CRBN in human HEK293 cells assessed as degradation of CDK7 at 0.01 to 10 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
4. | ALA4822297 | B | Protac activity at CDK7/CRBN in human HEK293 cells assessed as degradation of CDK7 at 1 uM measured upto 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
5. | ALA4822310 | B | Protac activity at CDK7/CRBN in human HEK293 cells assessed as degradation of CDK7 at 10 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA4822312 | B | Protac activity at CDK7/CRBN in human HEK293 cells assessed as degradation of CDK7 at 10 uM incubated for 24 hrs in presence of pomalidomide by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
7. | ALA4831164 | B | Protac activity at CRBN/CDK7 in human MDA-MB-231 cells assessed as induction of degradation of CDK7 at 0.01 to 2.5 uM incubated for 4 to 8 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
8. | ALA4831177 | B | Protac activity at CRBN/CDK7 in human MDA-MB-231 cells assessed as induction of degradation of CDK7 at 100 to 500 nM incubated for 4 to 8 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |