| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4313022 | A | Induction of CRBN-mediated CDK9 degradation in human U251 cells at 500 nM after 4 hrs by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA4341457 | B | Induction of CRBN-mediated CDK9 degradation in human MIAPaCa2 cells at 0.5 uM measured after 24 hrs by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4388613 | B | Protac activity at CRBN/CDK9 in human MOLT4 cells assessed as induction of CDK9 protein degradation after 6 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4388614 | B | Protac activity at CRBN/CDK9 in human MOLT4 cells assessed as induction of CDK9 protein degradation after 6 hrs by Western blot analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4388615 | B | Protac activity at CRBN/CDK9 in human HCT116 cells assessed as induction of CDK9 protein degradation after 6 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4388616 | B | Protac activity at CRBN/CDK9 in human HCT116 cells assessed as induction of CDK9 protein degradation at 20 uM after 6 hrs by Western blot analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4604222 | B | Protac activity at CRBN/CDK9 in AR-negative human PC3 cells assessed as induction of CDK9 protein degradation at 1 uM after 12 hrs by Western blot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 8. | ALA4604223 | B | Protac activity at CRBN/CDK9 in AR-negative human PC3 cells assessed as induction of CDK9 protein degradation at 30 uM after 12 hrs by Western blot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 9. | ALA4604225 | B | Protac activity at CRBN/CDK9 in AR-negative human PC3 cells assessed as induction of CDK9 protein degradation at 50 nM after 12 hrs by Western blot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 10. | ALA4604268 | B | Protac activity at CRBN/CDK9 in AR-negative human PC3 cells assessed as induction of CDK9 protein degradation at 5 uM after 12 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4701467 | B | Induction of CRBN-mediated CDK9 degradation in human HCT116 cells assessed as reduction in CDK9 level incubated for 6 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4701468 | B | Induction of CRBN-mediated CDK9 degradation in human MOLT4 cells incubated for 6 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4701469 | B | Induction of CRBN-mediated CDK9 degradation in human MCF-7 cells after 24 hrs by Western analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4819914 | B | Protac activity at CRBN/CDK9 in human MV4-11 cells assessed as CDK9 degradation rate at 500 nM incubated for 6 hrs by Western blot assay relative to control | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 15. | ALA4819915 | B | Protac activity at CRBN/CDK9 in human MOLM-13 cells assessed as CDK9 degradation rate at 500 nM incubated for 6 hrs by Western blot assay relative to control | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 16. | ALA4819916 | B | Protac activity at CRBN/CDK9 in human MV4-11 cells assessed as induction of CDK9 degradation incubated for 6 hrs by Western blot assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 17. | ALA4819917 | B | Protac activity at CRBN/CDK9 in human MV4-11 cells assessed as induction of CDK9 degradation by measuring downregulation of CDK9 expression level at 250 nM by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4819918 | B | Protac activity at CRBN/CDK9 in human MV4-11 cells assessed as induction of CDK9 degradation by measuring downregulation of MCL-1 protein expression level at 250 nM by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4819953 | B | Protac activity at CRBN/CDK9 in human MV4-11 cells assessed as induction of CDK9 degradation by measuring downregulation of CDK9 expression level at 250 nM measured after 1 hr by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4819954 | B | Protac activity at CRBN/CDK9 in human MV4-11 cells assessed as induction of CDK9 degradation by measuring MCL-1 protein expression level at 250 nM measured after 12 hrs by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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