# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4312978 | Binding | Induction of CRBN-mediated CDK6 degradation in human U251 cells after 24 hrs by immunoblot analysis | Homo sapiens | 20 | ALA4311951 | cell-based format | Scientific Literature | |
2. | ALA4312986 | Binding | Induction of CRBN-mediated CDK6 degradation in human U251 cells at 1 uM after 24 hrs by immunoblot analysis | Homo sapiens | 8 | ALA4311951 | cell-based format | Scientific Literature | |
3. | ALA4312988 | Binding | Induction of CRBN-mediated CDK6 degradation in human U251 cells assessed as CDK6 level at 0.1 nM by immunoblot analysis relative to control | Homo sapiens | 1 | ALA4311951 | cell-based format | Scientific Literature | |
4. | ALA4312989 | Binding | Induction of CRBN-mediated CDK6 degradation in human U251 cells assessed as CDK6 level at 0.33 nM by immunoblot analysis relative to control | Homo sapiens | 1 | ALA4311951 | cell-based format | Scientific Literature | |
5. | ALA4312990 | Binding | Induction of CRBN-mediated CDK6 degradation in human U251 cells assessed as CDK6 level at 1 nM by immunoblot analysis relative to control | Homo sapiens | 1 | ALA4311951 | cell-based format | Scientific Literature | |
6. | ALA4312991 | Binding | Induction of CRBN-mediated CDK6 degradation in human U251 cells assessed as CDK6 level at 3.3 nM by immunoblot analysis relative to control | Homo sapiens | 1 | ALA4311951 | cell-based format | Scientific Literature | |
7. | ALA4312992 | Binding | Induction of CRBN-mediated CDK6 degradation in human U251 cells assessed as CDK6 level at 10 nM by immunoblot analysis relative to control | Homo sapiens | 1 | ALA4311951 | cell-based format | Scientific Literature | |
8. | ALA4312993 | Binding | Induction of CRBN-mediated CDK6 degradation in human U251 cells assessed as CDK6 level at 33 nM by immunoblot analysis relative to control | Homo sapiens | 1 | ALA4311951 | cell-based format | Scientific Literature | |
9. | ALA4312994 | Binding | Induction of CRBN-mediated CDK6 degradation in human U251 cells assessed as CDK6 level at 100 nM by immunoblot analysis relative to control | Homo sapiens | 1 | ALA4311951 | cell-based format | Scientific Literature | |
10. | ALA4312995 | Binding | Induction of CRBN-mediated CDK6 degradation in human U251 cells assessed as CDK6 level at 330 nM by immunoblot analysis relative to control | Homo sapiens | 1 | ALA4311951 | cell-based format | Scientific Literature | |
11. | ALA4312996 | Binding | Induction of CRBN-mediated CDK6 degradation in human U251 cells assessed as CDK6 level at 1000 nM by immunoblot analysis relative to control | Homo sapiens | 1 | ALA4311951 | cell-based format | Scientific Literature | |
12. | ALA4312997 | Binding | Induction of CRBN-mediated CDK6 degradation in human U251 cells assessed as CDK6 level at 3300 nM by immunoblot analysis relative to control | Homo sapiens | 1 | ALA4311951 | cell-based format | Scientific Literature | |
13. | ALA4312998 | Binding | Induction of CRBN-mediated CDK6 degradation in human U251 cells assessed as CDK6 level at 10000 nM by immunoblot analysis relative to control | Homo sapiens | 1 | ALA4311951 | cell-based format | Scientific Literature | |
14. | ALA4313010 | Binding | Induction of CRBN-mediated CDK6 degradation in human U251 cells at 100 nM measured after 2 to 6 hrs by time-lapse analysis | Homo sapiens | 1 | ALA4311951 | cell-based format | Scientific Literature | |
15. | ALA4313012 | Binding | Induction of CRBN-mediated CDK6 degradation in human U251 cells at 100 nM after 24 hrs by immunoblot analysis | Homo sapiens | 3 | ALA4311951 | cell-based format | Scientific Literature | |
16. | ALA4313013 | Binding | Induction of CRBN-mediated CDK6 degradation in human U251 cells at 100 nM in presence of palbociclib after 24 hrs by immunoblot analysis | Homo sapiens | 1 | ALA4311951 | cell-based format | Scientific Literature | |
17. | ALA4313014 | Binding | Induction of CRBN-mediated CDK6 degradation in human U251 cells at 100 nM in presence of pomalidomide after 24 hrs by immunoblot analysis | Homo sapiens | 1 | ALA4311951 | cell-based format | Scientific Literature | |
18. | ALA4313015 | Binding | Induction of CRBN-mediated CDK6 degradation in human U251 cells at 500 nM in presence of proteasomal inhibitor carfilzomib after 8 hrs by immunoblot analysis | Homo sapiens | 1 | ALA4311951 | cell-based format | Scientific Literature | |
19. | ALA4313016 | Binding | Induction of CRBN-mediated CDK6 degradation in human U251 cells at 500 nM in presence of neddylation inhibitor MLN4924 after 8 hrs by immunoblot analysis | Homo sapiens | 1 | ALA4311951 | cell-based format | Scientific Literature | |
20. | ALA4313017 | Binding | Induction of CRBN-mediated CDK6 degradation in human U251 cells at 500 nM after 4 hrs by immunoblot analysis | Homo sapiens | 1 | ALA4311951 | cell-based format | Scientific Literature |