| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4313021 | A | Induction of CRBN-mediated CDK5 degradation in human U251 cells at 500 nM after 4 hrs by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA4341455 | B | Induction of CRBN-mediated CDK5 degradation in human MIAPaCa2 cells at 0.5 uM measured after 24 hrs by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4604257 | B | Protac activity at CRBN/CDK5 in AR-negative human PC3 cells assessed as induction of CDK5 protein degradation at 1 uM after 12 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA4822290 | B | Protac activity at CDK5/CRBN in human HEK293 cells assessed as degradation of CDK5 at 0.01 to 10 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4822299 | B | Protac activity at CDK5/CRBN in human HEK293 cells assessed as degradation of CDK5 at 1 uM measured upto 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4831162 | B | Protac activity at CRBN/CDK5 in human MDA-MB-231 cells assessed as induction of degradation of CDK5 at 0.01 to 2.5 uM incubated for 4 to 8 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4831175 | B | Protac activity at CRBN/CDK5 in human MDA-MB-231 cells assessed as induction of degradation of CDK5 at 100 to 500 nM incubated for 4 to 8 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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