# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4322319 | B | Induction of CRBN-mediated Bcl-xl degradation in human HeLa cells at 10 uM incubated for 12 hrs by Western blot analysis | Homo sapiens | 2 | ALA4321796 | cell-based format | Scientific Literature | |
2. | ALA4769813 | B | Protac activity at BCL-XL/CRBN in human MyLa1929 cells assessed as degradation of BCL-XL at 0.01 to 3 uM measured after 16 hrs by western blot analysis | Homo sapiens | 1 | ALA4765315 | cell-based format | Scientific Literature | |
3. | ALA5104687 | B | PROTAC activity at CRBN/BCL-XL in human WI-38 cells assessed as induction of BCL-XL degradation incubated for 16 hrs by Western blot analysis | Homo sapiens | 1 | ALA5104095 | cell-based format | Scientific Literature | |
4. | ALA5104688 | B | PROTAC activity at CRBN/BCL-XL in human WI-38 cells assessed as induction of BCL-XL degradation incubated for 16 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA5104095 | cell-based format | Scientific Literature | |
5. | ALA5108726 | B | PROTAC activity at CRBN/Bcl-xL in human MOLT-4 cells assessed as induction of Bcl-xL degradation incubated for 16 hrs by Western blot assay | Homo sapiens | 1 | ALA5107957 | cell-based format | Scientific Literature | |
6. | ALA5108727 | B | PROTAC activity at CRBN/Bcl-xL in human MOLT-4 cells assessed as induction of Bcl-xL degradation at 100 nM incubated for 16 hrs by Western blot assay relative to control | Homo sapiens | 1 | ALA5107957 | cell-based format | Scientific Literature | |
7. | ALA5215147 | B | PROTAC activity at CRBN/BCL-XL in human MOLT-4 cells assessed as induction of BCL-XL degradation incubated for 16 hrs by Western blot analysis | Homo sapiens | 1 | ALA5214885 | cell-based format | Scientific Literature |