# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4313026 | Binding | Induction of CRBN-mediated ZFP91 degradation in human U251 cells at 500 nM after 4 hrs by TMT Mass spectrometry based proteomic analysis | Homo sapiens | 1 | ALA4311951 | cell-based format | Scientific Literature | |
2. | ALA4313030 | Binding | Induction of CRBN-mediated ZFP91 degradation in human U251 cells at 500 nM after 24 hrs by immunoblot analysis | Homo sapiens | 1 | ALA4311951 | cell-based format | Scientific Literature | |
3. | ALA4712278 | Binding | Protac activity at CRBN/ZFP91 in human HT-29 cells assessed as induction of ZFP91 degradation up to 10 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4706631 | cell-based format | Scientific Literature | |
4. | ALA4713701 | Binding | Protac activity at CRBN/ZFP91 in human BxPC-3 cells assessed as induction of ZF91 degradation incubated for 24 hrs by western blot analysis | Homo sapiens | 1 | ALA4706672 | cell-based format | Scientific Literature | |
5. | ALA4713737 | Binding | Protac activity at CRBN/ZFP91 in human BxPC-3 cells assessed as induction of ZF91 degradation at 1 uM incubated for 16 hrs by western blot analysis | Homo sapiens | 1 | ALA4706672 | cell-based format | Scientific Literature | |
6. | ALA4713738 | Binding | Protac activity at CRBN/ZFP91 in human BxPC-3 cells assessed as induction of ZF91 degradation at upto 3 uM incubated for 16 hrs by western blot analysis | Homo sapiens | 1 | ALA4706672 | cell-based format | Scientific Literature | |
7. | ALA4713739 | Binding | Protac activity at CRBN/ZFP91 in human BxPC-3 cells assessed as induction of ZF91 degradation incubated for 16 hrs by western blot analysis | Homo sapiens | 1 | ALA4706672 | cell-based format | Scientific Literature | |
8. | ALA4713740 | Binding | Protac activity at CRBN/ZFP91 in human BxPC-3 cells assessed as induction of ZF91 degradation incubated for 4 hrs by western blot analysis | Homo sapiens | 1 | ALA4706672 | cell-based format | Scientific Literature | |
9. | ALA4713741 | Binding | Protac activity at CRBN/ZFP91 in human BxPC-3 cells assessed as ZF91 protein degradation at 1 uM incubated for 16 hrs in presence of proteasome inhibitor carfilzomib by western blot analysis | Homo sapiens | 1 | ALA4706672 | cell-based format | Scientific Literature | |
10. | ALA4713742 | Binding | Protac activity at CRBN/ZFP91 in human MIA PaCa-2 cells assessed as ZF91 protein degradation at 0.1 to 0.5 uM incubated for 16 hrs in presence of proteasome inhibitor carfilzomib by western blot analysis | Homo sapiens | 1 | ALA4706672 | cell-based format | Scientific Literature | |
11. | ALA4713743 | Binding | Protac activity at CRBN/ZFP91 in human BxPC-3 cells assessed as degradation of ZFP91 at 0.5 uM incubated for 16 hrs in presence of napabucasin by western blot analysis | Homo sapiens | 1 | ALA4706672 | cell-based format | Scientific Literature | |
12. | ALA4713779 | Binding | Protac activity at CRBN/ZFP91 in human BxPC-3 cells assessed as ZFP91 degradation incubated for 16 hrs by proteomic analysis | Homo sapiens | 1 | ALA4706672 | cell-based format | Scientific Literature | |
13. | ALA4713806 | Binding | Protac activity at CRBN/ZFP91 in human BxPC-3 cells assessed as alteration of ZF91 protein levels at 0.5 uM incubated for 16 hrs in presence of NQO1 inhibitor dicoumarol | Homo sapiens | 1 | ALA4706672 | cell-based format | Scientific Literature |