# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4322322 | B | Induction of CRBN-mediated Mcl-1 degradation in human HeLa cells assessed as relative abundance at 10 uM after 12 hrs by Western blot analysis (Rvb = 1 No_unit) | Homo sapiens | 14 | ALA4321796 | cell-based format | Scientific Literature | |
2. | ALA4322323 | B | Induction of CRBN-mediated Mcl-1 degradation in human HeLa cells assessed as relative abundance at 1 uM after 12 hrs by Western blot analysis (Rvb = 1 No_unit) | Homo sapiens | 12 | ALA4321796 | cell-based format | Scientific Literature | |
3. | ALA4322326 | B | Induction of CRBN-mediated Mcl-1 degradation in human HeLa cells at 10 uM after 12 hrs by Western blot analysis relative to control | Homo sapiens | 7 | ALA4321796 | cell-based format | Scientific Literature | |
4. | ALA4322328 | B | Induction of CRBN-mediated Mcl-1 degradation in human HeLa cells after 12 hrs by Western blot analysis | Homo sapiens | 1 | ALA4321796 | cell-based format | Scientific Literature | |
5. | ALA4322330 | B | Induction of CRBN-mediated Mcl-1 degradation in human HeLa cells assessed as formation of ubiquitin adducts of Mcl-1 at 1 to 10 uM after 12 hrs by Western blot analysis | Homo sapiens | 2 | ALA4321796 | cell-based format | Scientific Literature | |
6. | ALA4322331 | B | Induction of CRBN-mediated Mcl-1 degradation in human HeLa cells assessed as decrease in Mcl-1 level at 1 uM after 12 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA4321796 | cell-based format | Scientific Literature | |
7. | ALA4322332 | B | Induction of CRBN-mediated Mcl-1 degradation in human HeLa cells assessed as Mcl-1 level at 10 uM after 12 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA4321796 | cell-based format | Scientific Literature | |
8. | ALA4322337 | B | Induction of CRBN-mediated Mcl-1 degradation in human HeLa cells assessed as relative abundance at 0.1 uM after 12 hrs by Western blot analysis (Rvb = 1 No_unit) | Homo sapiens | 3 | ALA4321796 | cell-based format | Scientific Literature | |
9. | ALA4322339 | B | Induction of CRBN-mediated Mcl-1 degradation in human HeLa cells assessed as relative abundance at 0.3 uM after 12 hrs by Western blot analysis (Rvb = 1 No_unit) | Homo sapiens | 3 | ALA4321796 | cell-based format | Scientific Literature | |
10. | ALA4322340 | B | Induction of CRBN-mediated Mcl-1 degradation in human HeLa cells assessed as relative abundance at 3 uM after 12 hrs by Western blot analysis (Rvb = 1 No_unit) | Homo sapiens | 3 | ALA4321796 | cell-based format | Scientific Literature | |
11. | ALA4322341 | B | Induction of CRBN-mediated Mcl-1 degradation in human HeLa cells at 10 uM by Western blot analysis | Homo sapiens | 1 | ALA4321796 | cell-based format | Scientific Literature | |
12. | ALA4322342 | B | Induction of CRBN-mediated Mcl-1 degradation in human HeLa cells assessed as relative abundance at 10 uM measured at 2 hrs by Western blot analysis (Rvb = 1 No_unit) | Homo sapiens | 3 | ALA4321796 | cell-based format | Scientific Literature | |
13. | ALA4322344 | B | Induction of CRBN-mediated Mcl-1 degradation in human HeLa cells assessed as relative abundance at 10 uM measured at 4 hrs by Western blot analysis (Rvb = 1 No_unit) | Homo sapiens | 3 | ALA4321796 | cell-based format | Scientific Literature | |
14. | ALA4322345 | B | Induction of CRBN-mediated Mcl-1 degradation in human HeLa cells assessed as relative abundance at 10 uM measured at 8 hrs by Western blot analysis (Rvb = 1 No_unit) | Homo sapiens | 3 | ALA4321796 | cell-based format | Scientific Literature | |
15. | ALA4322347 | B | Induction of CRBN-mediated Mcl-1 degradation in human HeLa cells assessed as relative abundance at 10 uM measured at 16 hrs by Western blot analysis (Rvb = 1 No_unit) | Homo sapiens | 3 | ALA4321796 | cell-based format | Scientific Literature | |
16. | ALA4322348 | B | Induction of CRBN-mediated Mcl-1 degradation in human HeLa cells assessed as relative abundance at 10 uM measured at 20 hrs by Western blot analysis (Rvb = 1 No_unit) | Homo sapiens | 3 | ALA4321796 | cell-based format | Scientific Literature | |
17. | ALA4322349 | B | Induction of CRBN-mediated Mcl-1 degradation in human HeLa cells assessed as relative abundance at 10 uM measured at 24 hrs by Western blot analysis (Rvb = 1 No_unit) | Homo sapiens | 3 | ALA4321796 | cell-based format | Scientific Literature | |
18. | ALA4322355 | B | Induction of CRBN-mediated Mcl-1 degradation in human HeLa cells at 10 uM measured at 12 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA4321796 | cell-based format | Scientific Literature | |
19. | ALA4322356 | B | Induction of CRBN-mediated Mcl-1 degradation in human HeLa cells at 10 uM measured at 24 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA4321796 | cell-based format | Scientific Literature | |
20. | ALA4322357 | B | Induction of CRBN-mediated Mcl-1 degradation in human HeLa cells assessed as Mcl-1 removal activity measured at 12 hrs by Western blot analysis | Homo sapiens | 2 | ALA4321796 | cell-based format | Scientific Literature |