| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4416003 | B | Protac activity against VHL/KIT in human K562 cells assessed as reduction in Kit protein levels at 1 to 100 nM incubated for 16 hrs by by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA5152841 | B | PROTAC activity at VHL/c-KIT in human HL-60 cells assessed as reduction in c-KIT protein level at >10 uM measured at 24 to 48 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA5152848 | B | PROTAC activity at VHL/c-KIT in human HL-60 cells assessed as reduction in c-KIT protein level at 20 uM preincubated with VHL032 for 1 hrs followed by compound addition and measured after for 48 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA5152849 | B | PROTAC activity at VHL/c-KIT in human HL-60 cells assessed as reduction in c-KIT protein level at 10 uM measured for 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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