| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4312983 | B | Induction of MDM2-mediated CDK4 degradation in human U251 cells at 1 uM after 24 hrs by immunoblot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 2. | ALA4312984 | B | Induction of VHL-mediated CDK4 degradation in human U251 cells at 1 uM after 24 hrs by immunoblot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 3. | ALA4628826 | B | Protac activity at CDK4/VHL in human Jurkat cells assessed as induction of CDK4 degradation measured after 24 hrs by capillary electrophoresis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 4. | ALA4628832 | B | Protac activity at CDK4/VHL in human epoxomicin pretreated Jurkat cells assessed as decrease in CDK4 protein level measured after 5 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4840233 | B | Protac activity at VHL/CDK4 in human MM1.S cells assessed as induction of CDK4 degradation at 0.1 to 1 uM measured after 16 hrs by Western blotting analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 6. | ALA4840240 | B | Protac activity at VHL/CDK4 in human MM1.S cells assessed as protein levels at 1 uM measured after 6 hrs by Western blot analysis relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 7. | ALA4840241 | B | Protac activity at VHL/CDK4 in human MM1.S cells assessed as protein levels at 1 uM measured after 72 hrs by Western blot analysis relative to control | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 8. | ALA5137688 | B | Protac activity at VHL/CDK4 in human MM1.S cells assessed as degradation of CDK4 measured after 16 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature |
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