#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4324543	B	Protac activity against VHL/MEK2 in human HT-29 cells harboring BRAF V600E variant assessed as degradation of MEK2 at 0.3 to 3 uM after 24 hrs by Western blot analysis	Homo sapiens	3	ALA4321854	cell-based format	Scientific Literature
2.	ALA4324549	B	Protac activity against VHL/MEK2 in human HT-29 cells harboring BRAF V600E variant assessed as degradation of MEK2 after 24 hrs by Western blot analysis	Homo sapiens	1	ALA4321854	cell-based format	Scientific Literature
3.	ALA4324551	B	Protac activity against VHL/MEK2 in human SK-MEL-28 cells harboring BRAF V600E variant assessed as degradation of MEK2 after 24 hrs by Western blot analysis	Homo sapiens	1	ALA4321854	cell-based format	Scientific Literature
4.	ALA4324553	B	Protac activity against VHL/MEK2 in human COLO205 cells harboring BRAF V600E variant assessed as degradation of MEK2 after 24 hrs by Western blot analysis	Homo sapiens	1	ALA4321854	cell-based format	Scientific Literature
5.	ALA4324555	B	Protac activity against VHL/MEK2 in human UACC257 cells harboring BRAF V600E variant assessed as degradation of MEK2 after 24 hrs by Western blot analysis	Homo sapiens	1	ALA4321854	cell-based format	Scientific Literature
6.	ALA4324557	B	Protac activity against VHL/MEK2 in human HT-29 cells harboring BRAF V600E variant assessed as degradation of MEK2 by measuring reduction in MEK2 protein level at 0.5 uM after 24 hrs by Western blot analysis relative to control	Homo sapiens	1	ALA4321854	cell-based format	Scientific Literature
7.	ALA4324559	B	Protac activity against VHL/MEK2 in human SK-MEL-28 cells harboring with BRAF V600E variant assessed as degradation of MEK2 by measuring reduction in MEK2 protein level at 0.3 uM after 24 hrs by Western blot analysis relative to control	Homo sapiens	1	ALA4321854	cell-based format	Scientific Literature
8.	ALA4324561	B	Protac activity against VHL/MEK2 in human HT-29 cells harboring with BRAF V600E variant assessed as degradation of MEK2 at 3 to 5 uM after 24 hrs by Western blot analysis	Homo sapiens	1	ALA4321854	cell-based format	Scientific Literature
9.	ALA4324563	B	Protac activity against VHL/MEK2 in human SK-MEL-28 cells harboring with BRAF V600E variant assessed as degradation of MEK2 at 3 to 5 uM after 24 hrs by Western blot analysis	Homo sapiens	1	ALA4321854	cell-based format	Scientific Literature
10.	ALA4324565	B	Protac activity against VHL/MEK2 in human COLO205 cells harboring with BRAF V600E variant assessed as degradation of MEK2 at 3 to 5 uM after 24 hrs by Western blot analysis	Homo sapiens	1	ALA4321854	cell-based format	Scientific Literature
11.	ALA4324567	B	Protac activity against VHL/MEK2 in human UACC257 cells harboring with BRAF V600E variant assessed as degradation of MEK2 at 3 to 5 uM after 24 hrs by Western blot analysis	Homo sapiens	1	ALA4321854	cell-based format	Scientific Literature
12.	ALA4324581	B	Protac activity against VHL/MEK2 in human HT-29 cells harboring with BRAF V600E variant assessed as degradation of MEK2 by measuring MEK2 protein level up to 1 uM after 24 hrs by Western blot analysis	Homo sapiens	2	ALA4321854	cell-based format	Scientific Literature
13.	ALA4324583	B	Protac activity against VHL/MEK2 in human SK-MEL-28 cells harboring with BRAF V600E variant assessed as degradation of MEK2 by measuring MEK2 protein level up to 1 uM after 24 hrs by Western blot analysis	Homo sapiens	2	ALA4321854	cell-based format	Scientific Literature
14.	ALA4324589	B	Protac activity against VHL/MEK2 in human HT-29 cells harboring with BRAF V600E variant assessed as degradation of MEK2 by measuring reduction in MEK2 protein level at 0.1 to 0.3 uM after 2 hrs by Western blot analysis	Homo sapiens	1	ALA4321854	cell-based format	Scientific Literature
15.	ALA4324591	B	Protac activity against VHL/MEK2 in human SK-MEL-28 cells harboring with BRAF V600E variant assessed as degradation of MEK2 by measuring reduction in MEK2 protein level at 0.1 to 0.3 uM after 2 hrs by Western blot analysis	Homo sapiens	1	ALA4321854	cell-based format	Scientific Literature
16.	ALA4324597	B	Protac activity against VHL/MEK2 in human HT-29 cells harboring with BRAF V600E variant assessed as degradation of MEK2 at 0.1 to 0.3 uM after 4 hrs by Western blot analysis	Homo sapiens	1	ALA4321854	cell-based format	Scientific Literature
17.	ALA4324599	B	Protac activity against VHL/MEK2 in human SK-MEL-28 cells harboring with BRAF V600E variant assessed as degradation of MEK2 at 0.1 to 0.3 uM after 4 hrs by Western blot analysis	Homo sapiens	1	ALA4321854	cell-based format	Scientific Literature
18.	ALA4324605	B	Protac activity against VHL/MEK2 in human HT-29 cells harboring with BRAF V600E variant assessed as degradation of MEK2 at 0.3 uM after 3 to 144 hrs by Western blot analysis	Homo sapiens	1	ALA4321854	cell-based format	Scientific Literature
19.	ALA4324611	B	Protac activity against VHL/MEK2 in human HT-29 cells harboring with BRAF V600E variant assessed as degradation of MEK2 by measuring MEK2 protein level at 0.3 uM pretreated with MEK1/2 inhibitor, PD0325901 for 2 hrs followed by incubation with compound for 10 hrs by Western blot analysis	Homo sapiens	1	ALA4321854	cell-based format	Scientific Literature
20.	ALA4324613	B	Protac activity against VHL/MEK2 in human SK-MEL-28 cells harboring with BRAF V600E variant assessed as degradation of MEK2 by measuring MEK2 protein level at 0.3 uM pretreated with MEK1/2 inhibitor, PD0325901 for 2 hrs followed by incubation with compound for 10 hrs by Western blot analysis	Homo sapiens	1	ALA4321854	cell-based format	Scientific Literature