| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4388601 | B | Protac activity at VHL/FLT3 in human MOLM14 cells assessed as induction of FLT3 protein degradation measured after 4 hrs by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA4388602 | B | Protac activity at VHL/FLT3 in human MOLM14 cells assessed as induction of FLT3 protein degradation at 50 nM measured after 4 hrs by immunoblot analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4686168 | B | Protac activity at VHL/FLT3 in human SR cells assessed as induction of FLT3 degradation | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA5152838 | B | PROTAC activity at VHL/FLT-3 in human HL-60 cells assessed as reduction in FLT-3 protein level at 10 to 20 uM incubated for 48 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA5152839 | B | PROTAC activity at VHL/FLT-3 in human HL-60 cells assessed as reduction in FLT-3 protein level at 10 uM incubated for 12 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA5152840 | B | PROTAC activity at VHL/FLT-3 in human HL-60 cells assessed as reduction in FLT-3 protein level at 10 uM by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA5152842 | B | PROTAC activity at VHL/FLT-3 in human K562 cells assessed as reduction in FLT-3 protein level at 20 uM incubated for 48 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA5152843 | B | PROTAC activity at VHL/FLT-3 in human HL-60 cells assessed as reduction in FLT-3 protein level at 1 uM incubated for 1 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA5152844 | B | PROTAC activity at VHL/FLT-3 in human HL-60 cells assessed as reduction in FLT-3 protein level at 1 uM incubated for 48 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA5152845 | B | PROTAC activity at VHL/FLT-3 in human HL-60 cells assessed as reduction in FLT-3 protein level at 20 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA5152846 | B | PROTAC activity at VHL/FLT-3 in human HL-60 cells assessed as reduction in FLT-3 protein level at 20 uM preincubated with MG-132 for 1 hrs followed by compound addition and measured after for 48 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA5152847 | B | PROTAC activity at VHL/FLT-3 in human HL-60 cells assessed as reduction in FLT-3 protein level at 20 uM preincubated with VHL032 for 1 hrs followed by compound addition and measured after for 48 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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