| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5249938 | B | Protac activity at VHL/CDK6 in human MM1.S cells assessed as degradation of CDK6 incubated for 16 hrs by immunoblot assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA4312981 | B | Induction of VHL-mediated CDK6 degradation in human U251 cells at 1 uM after 24 hrs by immunoblot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 3. | ALA4313063 | B | Induction of VHL-mediated CDK6 degradation in human DAOY cells at 1 uM after 24 hrs by immunoblot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 4. | ALA4628827 | B | Protac activity at CDK6/VHL in human Jurkat cells assessed as induction of CDK6 degradation measured after 24 hrs by capillary electrophoresis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA4628833 | B | Protac activity at CDK6/VHL in human epoxomicin pretreated Jurkat cells assessed as decrease in CDK4 protein level measured after 5 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4840234 | B | Protac activity at VHL/CDK6 in human MM1.S cells assessed as induction of CDK6 degradation at 0.1 to 1 uM measured after 16 hrs by Western blotting analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 7. | ALA4840238 | B | Protac activity at VHL/CDK6 in human MM1.S cells assessed as protein levels at 1 uM measured after 6 hrs by Western blot analysis relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 8. | ALA4840239 | B | Protac activity at VHL/CDK6 in human MM1.S cells assessed as protein levels at 1 uM measured after 72 hrs by Western blot analysis relative to control | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 9. | ALA5104676 | B | PROTAC activity at VHL/CDK6 in human MM1.S cells assessed as induction of CDK6 degradation incubated for 16 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA5104677 | B | PROTAC activity at VHL/CDK6 in human MM1.S cells assessed as induction of CDK6 degradation at 0.1 to 1 uM incubated for 16 hrs by Western blot analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA5137687 | B | Protac activity at VHL/CDK6 in human MM1.S cells assessed as degradation of CDK6 measured after 16 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA5137689 | B | Protac activity at VHL/CDK6 in human MM1.S cells assessed as degradation of CDK6 at 100 nM relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature |
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