#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4361879	Binding	Protac activity at VHL/IRAK4 in human PBMC assessed as induction of degradation of IRAK4 incubated for 24 hrs by Western blot analysis	Homo sapiens	2	ALA4359855	protein format	Scientific Literature
2.	ALA4361880	Binding	Protac activity at VHL/IRAK4 in human PBMC assessed as induction of degradation of IRAK4 at 3 uM incubated for 24 hrs by Western blot analysis relative to control	Homo sapiens	1	ALA4359855	protein format	Scientific Literature
3.	ALA4361886	Binding	Protac activity at VHL/IRAK4 in human epoxomicin PBMC assessed as increase in p21 accumulation at 0.01 to 10 uM incubated for 22 hrs by Western blot analysis	Homo sapiens	1	ALA4359855	protein format	Scientific Literature
4.	ALA4361887	Binding	Protac activity at VHL/IRAK4 in human PBMC assessed as reduction in R848-stimulated IL-1beta level preincubated for 18 hrs followed by R848-stimulation and measured after 8 hrs by MSD assay	Homo sapiens	2	ALA4359855	protein format	Scientific Literature
5.	ALA4361888	Binding	Protac activity at VHL/IRAK4 in human PBMC assessed as reduction in R848-stimulated IFNgamma preincubated for 18 hrs followed by R848 stimulation and measured after 8 hrs by MSD assay	Homo sapiens	2	ALA4359855	protein format	Scientific Literature
6.	ALA4361889	Binding	Protac activity at VHL/IRAK4 in human PBMC assessed as reduction in R848-stimulated IL-6 level preincubated for 18 hrs followed by R848 stimulation and measured after 8 hrs by MSD assay	Homo sapiens	2	ALA4359855	protein format	Scientific Literature
7.	ALA4361890	Binding	Protac activity at VHL/IRAK4 in human PBMC assessed as reduction in R848-stimulated IL-8 level preincubated for 18 hrs followed by R848 stimulation and measured after 8 hrs by MSD assay	Homo sapiens	2	ALA4359855	protein format	Scientific Literature
8.	ALA4361891	Binding	Protac activity at VHL/IRAK4 in human PBMC assessed as reduction in R848-stimulated IL-10 level preincubated for 18 hrs followed by R848 stimulation and measured after 8 hrs by MSD assay	Homo sapiens	2	ALA4359855	protein format	Scientific Literature
9.	ALA4361892	Binding	Protac activity at VHL/IRAK4 in human PBMC assessed as reduction in R848-stimulated TNFalpha level preincubated for 18 hrs followed by R848 stimulation and measured after 8 hrs by MSD assay	Homo sapiens	2	ALA4359855	protein format	Scientific Literature
10.	ALA4361893	Binding	Protac activity at VHL/IRAK4 in human dermal fibroblast assessed as induction of degradation of IRAK4 incubated for 24 hrs by Western blot analysis	Homo sapiens	1	ALA4359855	protein format	Scientific Literature
11.	ALA4361894	Binding	Protac activity at VHL/IRAK4 in human dermal fibroblast assessed as reduction in IL-1beta stimulated IL-6 level at 300 nM incubated for 18 hrs followed by IL-1beta stimulation further incubated for 8 hrs by MSD assay	Homo sapiens	2	ALA4359855	protein format	Scientific Literature
12.	ALA4361895	Binding	Protac activity at VHL/IRAK4 in human PBMC assessed as induction of degradation of IRAK4 incubated for 24 hrs by Western blot analysis relative to control	Homo sapiens	1	ALA4359855	protein format	Scientific Literature
13.	ALA4361899	Binding	Protac activity at VHL/IRAK4 in human THP-1 cells assessed as induction of degradation of IRAK4 at 0.1 to 10 uM incubated for 24 hrs by Western blot analysis	Homo sapiens	7	ALA4359855	cell-based format	Scientific Literature
14.	ALA4361900	Binding	Protac activity at VHL/IRAK4 in human PBMC assessed as remaining IRAK4 level at 100 nM incubated for 24 hrs by Western blot analysis relative to control	Homo sapiens	1	ALA4359855	protein format	Scientific Literature
15.	ALA4361901	Binding	Protac activity at VHL/IRAK4 in human PBMC assessed as remaining IRAK4 level at 300 nM incubated for 24 hrs by Western blot analysis relative to control	Homo sapiens	1	ALA4359855	protein format	Scientific Literature
16.	ALA4361902	Binding	Protac activity at VHL/IRAK4 in human PBMC assessed as remaining IRAK4 level at 1 uM incubated for 24 hrs by Western blot analysis relative to control	Homo sapiens	1	ALA4359855	protein format	Scientific Literature
17.	ALA4361903	Binding	Protac activity at VHL/IRAK4 in human PBMC assessed as remaining IRAK4 level at 10 uM incubated for 24 hrs by Western blot analysis relative to control	Homo sapiens	1	ALA4359855	protein format	Scientific Literature
18.	ALA4361904	Binding	Protac activity at VHL/IRAK4 in human epoxomicin pretreated PBMC assessed as induction of degradation of IRAK4 at 0.01 to 10 uM incubated for 22 hrs by Western blot analysis	Homo sapiens	1	ALA4359855	protein format	Scientific Literature