# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA775438 | F | Induction of cytochrome P-450 enzyme was evaluated in units of nmol of enzyme/mg liver of chronic treated rats | 1 | ALA1129543 | assay format | Scientific Literature | ||
2. | ALA4000779 | A | Metabolic stability in rat liver microsomes assessed as NADPH CYP450 reductase-mediated compound metabolism by measuring compound remaining in presence of NADPH at 20 uM after 30 mins by HPLC | Rattus norvegicus | 11 | ALA4000171 | assay format | Scientific Literature | |
3. | ALA4000780 | A | Metabolic stability in rat liver S9 fraction assessed as NADPH CYP450 reductase-mediated compound metabolism by measuring compound remaining in presence of NADPH at 20 uM after 30 mins by HPLC method | Rattus norvegicus | 11 | ALA4000171 | assay format | Scientific Literature | |
4. | ALA4042827 | A | Drug metabolism in pH 7.4 PBS assessed as rat P450 oxidoreductase-mediated compound hydrolysis preincubated for 20 mins followed by protocatechuate 3,4-dioxygenase addition to create anoxic condition and subsequent addition of P450 oxidoreductase in presence of NADPH after 24 hrs by HPLC method | Rattus norvegicus | 3 | ALA4041538 | single protein format | Scientific Literature | |
5. | ALA4612126 | B | Substrate activity at rat NADPH-cytochrome P450 oxidoreductase expressed in supersomes assessed as compound cleavage after 24 hrs in anaerobic condition by HPLC analysis | Rattus norvegicus | 1 | ALA4610093 | assay format | Scientific Literature | |
6. | ALA4612127 | B | Substrate activity at rat NADPH-cytochrome P450 oxidoreductase expressed in supersomes assessed as compound cleavage after 90 mins in anaerobic condition by HPLC analysis | Rattus norvegicus | 15 | ALA4610093 | assay format | Scientific Literature |