| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA750985 | F | The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 4 (P2X4) at 10 uM | 1 | assay format | Scientific Literature | |||
| 2. | ALA750986 | F | Antagonist activity against recombinant rat P2X purinoceptor 4 (P2X4) at 3 uM, expressed in Xenopus oocytes | 5 | cell-based format | Scientific Literature | |||
| 3. | ALA750987 | F | Antagonist activity against recombinant rat P2X purinoceptor 4 (P2X4) at 30 uM, expressed in Xenopus oocytes | 5 | cell-based format | Scientific Literature | |||
| 4. | ALA750988 | F | The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 4 (P2X4) 3 uM | 1 | assay format | Scientific Literature | |||
| 5. | ALA750989 | F | The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 4 (P2X4) at 3 uM | 1 | assay format | Scientific Literature | |||
| 6. | ALA751126 | F | Inhibition of inward ion current elicited by ATP at rat P2X4 receptor (mutant type) | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
| 7. | ALA751127 | F | Inhibition of inward ion current elicited by ATP at rat P2X4 receptor (wild type) | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
| 8. | ALA759520 | F | The compound was evaluated for antagonist activity against P2X purinoceptor 1 (P2X1) receptor from rat vas deferens | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
| 9. | ALA759521 | B | Dissociation constant of the compound at P2X purinoceptor 1 (P2X1) from rat vas deferens was reported | Rattus norvegicus | 1 | single protein format | Scientific Literature | ||
| 10. | ALA872171 | F | Inhibitory concentration against rat P2X purinoceptor 1 expressed in Xenopus laevis oocytes | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA872174 | F | Inhibitory concentration against rat P2X purinoceptor 4 expressed in Xenopus laevis oocytes | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA1680809 | F | Antagonist activity against rat P2X4 receptor expressed in Xenopus laevis oocyte assessed as inhibition of alpha, beta-meATP-induced inward current by two-electrode voltage-clamp electrophysiology | Rattus norvegicus | 62 | assay format | Scientific Literature | ||
| 13. | ALA2184470 | F | Antagonist activity at rat P2X4 receptor by cell-based calcium influx assay | Rattus norvegicus | 11 | cell-based format | Scientific Literature | ||
| 14. | ALA2184485 | F | Antagonist activity at rat P2X4 receptor at 10 uM by cell-based calcium influx assay | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
| 15. | ALA3108481 | B | Antagonist activity at rat P2X4 receptor assessed as inhibition of ATP-induced calcium influx preincubated for 30 mins followed by ATP addition by Fluo-4 AM dye-based fluorescence assay | Rattus norvegicus | 6 | single protein format | Scientific Literature | ||
| 16. | ALA4031269 | B | Inhibition of rat P2X4 receptor expressed in xenopus lavies oocytes assessed as inhibition of ATP-induced peak current at 3 mM by two electrode voltage clamp | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4324780 | B | Antagonist activity at rat P2X4 receptor tranfected in human 1321N1 cells assessed as inhibition of Mg-ATP-induced calcium influx incubated for 30 mins and measured every 2 secs for 120 secs by Fluo8-AM staining based FLIPR assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4324808 | B | Antagonist activity at rat P2X4 receptor tranfected in human 1321N1 cells assessed as inhibition of ATP-induced calcium influx incubated for 10 mins by Fluo2-AM staining based inverted fluorescence microscopic method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4714128 | B | Antagonist activity at rat P2X4 receptor expressed in Xenopus laevis oocytes assessed as reduction in ATP-induced channel currents at 100 uM by TEVC electrophysiology assay relative to control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA5106946 | B | Antagonist activity at rat P2X4R expressed in HEK293 cells preincubated for 2 mins followed by ATP addition and measured after 4 mins | Rattus norvegicus | 1 | cell-based format | Scientific Literature |
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