# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4830744 | Functional | Agonist activity at human GPR27 expressed in HEK293 cells co-expressing FnLArrb2.GPR27V2LFc assessed as induction of beta-arrestin recruitment incubated for 10 mins measured followed by addition of D-luciferin by firefly-luciferase complementation assay | Homo sapiens | 31 | ALA4828750 | cell-based format | Scientific Literature | |
2. | ALA4830745 | Functional | Agonist activity at human GPR27 expressed in HEK293 cells co-expressing FnLArrb2.GPR27V2LFc assessed as maximal induction of beta-arrestin recruitment incubated for 10 mins measured followed by addition of D-luciferin by firefly-luciferase complementation assay relative to control | Homo sapiens | 31 | ALA4828750 | cell-based format | Scientific Literature | |
3. | ALA4830747 | Functional | Agonist activity at human GPR27 expressed in HEK293 cells assessed as induction of beta-arrestin recruitment pretreated with substrate for 45 mins followed by compound addition and measured for 40 mins by NanoLuc luciferase complementation assay | Homo sapiens | 2 | ALA4828750 | cell-based format | Scientific Literature | |
4. | ALA4883443 | Binding | PRESTO-Tango GPCRome screening (GPR27) | 1 | ALA4507309 | single protein format | Donated Chemical Probes - SGC Frankfurt |