| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4323176 | B | Inhibition of N-(fluorescein-5-yl)-N'-(alpha-L-fucopyranosyl ethylen)thiocarbamide binding to Pseudomonas aeruginosa PAO1 LecB incubated for 22 to 24 hrs by fluorescence polarization assay | Pseudomonas aeruginosa PAO1 | 29 | ALA4321818 | single protein format | Scientific Literature | |
| 2. | ALA4323177 | B | Inhibition of N-(fluorescein-5-yl)-N'-(alpha-L-fucopyranosyl ethylen)thiocarbamide binding to Pseudomonas aeruginosa PA14 LecB incubated for 22 to 24 hrs by fluorescence polarization assay | Pseudomonas aeruginosa PA14 | 29 | ALA4321818 | single protein format | Scientific Literature | |
| 3. | ALA4323178 | B | Binding affinity to Pseudomonas aeruginosa PAO1 LecB by isothermal titration calorimetry | Pseudomonas aeruginosa PAO1 | 1 | ALA4321818 | single protein format | Scientific Literature | |
| 4. | ALA4323179 | B | Binding affinity to Pseudomonas aeruginosa PA14 LecB by isothermal titration calorimetry | Pseudomonas aeruginosa PA14 | 1 | ALA4321818 | single protein format | Scientific Literature | |
| 5. | ALA4323188 | B | Inhibition of Pseudomonas aeruginosa PAO1 LecB after 6 hrs by fluorescence polarization assay | Pseudomonas aeruginosa PAO1 | 14 | ALA4321818 | single protein format | Scientific Literature | |
| 6. | ALA4323189 | B | Competitive inhibition of N-(fluorescein-5-yl)-N'-(alpha-L-fucopyranosyl ethylen)-thiocarbamide binding to Pseudomonas aeruginosa PA14 LecB after 8 to 22 hrs by fluorescence polarization assay | Pseudomonas aeruginosa PA14 | 14 | ALA4321818 | single protein format | Scientific Literature | |
| 7. | ALA4326938 | B | Inhibition of N-(Fluorescein-5-yl)-N'-(alpha-L-fucopyranosyl ethylen)thiocarbamide binding to Pseudomonas aeruginosa PAO1 LecB after 22 to 24 hrs by fluorescence polarization assay | Pseudomonas aeruginosa PAO1 | 2 | ALA4325854 | single protein format | Scientific Literature | |
| 8. | ALA4326939 | B | Inhibition of N-(Fluorescein-5-yl)-N'-(alpha-L-fucopyranosyl ethylen)thiocarbamide binding to Pseudomonas aeruginosa PA14 LecB after 22 to 24 hrs by fluorescence polarization assay | Pseudomonas aeruginosa PA14 | 2 | ALA4325854 | single protein format | Scientific Literature | |
| 9. | ALA4326940 | B | Inhibition of biotinylated polymeric fucose binding to Pseudomonas aeruginosa LecB expressed in Escherichia coli BL21(DE3) preincubated for 1 hr followed by biotinylated polymeric fucose addition and measured after 1 hr | Pseudomonas aeruginosa | 1 | ALA4325854 | assay format | Scientific Literature | |
| 10. | ALA4326975 | B | Inhibition of Pseudomonas aeruginosa LecB | Pseudomonas aeruginosa | 1 | ALA4325854 | single protein format | Scientific Literature | |
| 11. | ALA4326976 | B | Binding affinity to Pseudomonas aeruginosa LecB | Pseudomonas aeruginosa | 1 | ALA4325854 | single protein format | Scientific Literature | |
| 12. | ALA4326977 | B | Binding affinity to Pseudomonas aeruginosa LecB assessed as dissociation half life | Pseudomonas aeruginosa | 1 | ALA4325854 | single protein format | Scientific Literature | |
| 13. | ALA4337366 | B | Inhibition of Pseudomonas aeruginosa LecB by fluorescence polarization assay | Pseudomonas aeruginosa | 7 | ALA4334486 | single protein format | Scientific Literature | |
| 14. | ALA4337367 | B | Potency index, ratio of IC50 for Me-alpha-L-fucoside to IC50 for test compound for inhibition of Pseudomonas aeruginosa LecB by fluorescence polarization assay | Pseudomonas aeruginosa | 1 | ALA4334486 | single protein format | Scientific Literature | |
| 15. | ALA4337368 | B | Potency index, ratio of IC50 for Me-alpha-D-mannoside to IC50 for test compound for inhibition of Pseudomonas aeruginosa LecB by fluorescence polarization assay | Pseudomonas aeruginosa | 1 | ALA4334486 | single protein format | Scientific Literature | |
| 16. | ALA5031840 | B | Binding affinity to recombinant Pseudomonas aeruginosa lecB expressed in Escherichia coli assessed as dissociation constant by isothermal titration calorimetry | Pseudomonas aeruginosa | 3 | ALA5030542 | assay format | Scientific Literature | |
| 17. | ALA5031842 | B | Binding affinity to recombinant Pseudomonas aeruginosa LecB expressed in Escherichia coli assessed as gibbs free energy change by isothermal titration calorimetry | Pseudomonas aeruginosa | 3 | ALA5030542 | assay format | Scientific Literature | |
| 18. | ALA5031844 | B | Binding affinity to recombinant Pseudomonas aeruginosa LecB expressed in Escherichia coli assessed as change in enthalpy by isothermal titration calorimetry | Pseudomonas aeruginosa | 3 | ALA5030542 | assay format | Scientific Literature | |
| 19. | ALA5031846 | B | Binding affinity to recombinant Pseudomonas aeruginosa LecB expressed in Escherichia coli assessed as change in entropy by isothermal titration calorimetry | Pseudomonas aeruginosa | 3 | ALA5030542 | assay format | Scientific Literature | |
| 20. | ALA5112265 | B | Competitive binding affinity to recombinant Pseudomonas aeruginosa PA14 LecB expressed in Escherichia coli BL21(DE3) incubated for 4 to 8 hrs by fluorescent polarization assay | Pseudomonas aeruginosa | 5 | ALA5108061 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!