| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4431090 | B | Binding affinity to HIV1 MA expressed in bacterial expression system assessed as inhibition of protein binding to Sel15 RNA at 100 uM preincubated for 30 mins followed by Sel15 RNA addition measured after 30 mins by electrophoretic mobility shift assay | Human immunodeficiency virus 1 | 15 | ALA4428129 | assay format | Scientific Literature | |
| 2. | ALA4431094 | B | Induction of HIV1 MA cross linking assessed as formation of protein dimer at 50 uM after 2 hrs by immunoblot analysis | Human immunodeficiency virus 1 | 15 | ALA4428129 | single protein format | Scientific Literature | |
| 3. | ALA4431113 | B | Binding affinity to HIV1 MA expressed in bacterial expression system assessed as inhibition of protein binding to Sel15 RNA at 50 uM preincubated for 30 mins followed by Sel15 RNA addition measured after 30 mins in presence of glutathione by electrophoretic mobility shift assay | Human immunodeficiency virus 1 | 1 | ALA4428129 | assay format | Scientific Literature | |
| 4. | ALA4431114 | B | Binding affinity to HIV1 MA expressed in bacterial expression system assessed as inhibition of protein binding to Sel15 RNA at 50 uM preincubated for 30 mins followed by Sel15 RNA addition measured after 30 mins in presence of cysteine by electrophoretic mobility shift assay | Human immunodeficiency virus 1 | 1 | ALA4428129 | assay format | Scientific Literature | |
| 5. | ALA4431115 | B | Binding affinity to HIV1 MA expressed in bacterial expression system assessed as inhibition of protein binding to Sel15 RNA at 50 uM preincubated for 30 mins followed by Sel15 RNA addition measured after 30 mins in presence of beta-mercaptoethanol by electrophoretic mobility shift assay | Human immunodeficiency virus 1 | 1 | ALA4428129 | assay format | Scientific Literature | |
| 6. | ALA4431118 | B | Binding affinity to HIV1 MA expressed in bacterial expression system assessed as inhibition of protein binding to Sel15 RNA at 50 uM preincubated for 30 mins followed by Sel15 RNA addition measured after 30 mins in presence of DTT by electrophoretic mobility shift assay | Human immunodeficiency virus 1 | 1 | ALA4428129 | assay format | Scientific Literature | |
| 7. | ALA4431119 | B | Binding affinity to HIV1 MA expressed in bacterial expression system assessed as inhibition of protein binding to Sel15 RNA at 50 uM preincubated for 30 mins followed by Sel15 RNA addition measured after 30 mins in presence of TCEP by electrophoretic mobility shift assay | Human immunodeficiency virus 1 | 1 | ALA4428129 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!