| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4383216 | ADME | Drug metabolism in human liver microsome S9 fraction assessed as UGT-mediated metabolism by measuring compound remaining at 5 uM pretreated with UDPGA and measured after 15 mins by UPLC-MS/MS analysis | Homo sapiens | 3 | ALA4382200 | microsome format | Scientific Literature | |
| 2. | ALA4383217 | ADME | Drug metabolism in human liver microsome S9 fraction assessed as UGT-mediated metabolism by measuring compound remaining at 5 uM pretreated with UDPGA and measured after 30 mins by UPLC-MS/MS analysis | Homo sapiens | 3 | ALA4382200 | microsome format | Scientific Literature | |
| 3. | ALA4383218 | ADME | Drug metabolism in human liver microsome S9 fraction assessed as UGT-mediated metabolism by measuring compound remaining at 5 uM pretreated with UDPGA and measured after 60 mins by UPLC-MS/MS analysis | Homo sapiens | 3 | ALA4382200 | microsome format | Scientific Literature | |
| 4. | ALA4378683 | ADME | Drug metabolism assessed as human UGT-mediated metabolism by measuring half life for DHD1 formation | Homo sapiens | 1 | ALA4376826 | protein format | Scientific Literature | |
| 5. | ALA4378684 | ADME | Drug metabolism assessed as human UGT-mediated metabolism by measuring half life for DHD3 formation | Homo sapiens | 1 | ALA4376826 | protein format | Scientific Literature | |
| 6. | ALA4378685 | ADME | Drug metabolism assessed as human UGT-mediated metabolism by measuring intrinsic clearance | Homo sapiens | 2 | ALA4376826 | protein format | Scientific Literature | |
| 7. | ALA4339708 | ADME | Drug metabolism in human hepatocytes assessed as UGT-mediated glucuronidation by measuring O-glucuronide formation at 10 uM measured after 4 hrs by LC-MS analysis | Homo sapiens | 1 | ALA4339197 | cell-based format | Scientific Literature | |
| 8. | ALA4362183 | ADME | Microsomal stability in human liver microsomes assessed as UGT-mediated metabolism by measuring compound remaining at 5 uM and measured for 15 mins in presence of UDPGA by UPLC-MS/MS analysis (Rvb = 100%) | Homo sapiens | 7 | ALA4359864 | microsome format | Scientific Literature | |
| 9. | ALA4362184 | ADME | Microsomal stability in human liver microsomes assessed as UGT-mediated metabolism by measuring compound remaining at 5 uM and measured for 30 mins in presence of UDPGA by UPLC-MS/MS analysis (Rvb = 100%) | Homo sapiens | 7 | ALA4359864 | microsome format | Scientific Literature | |
| 10. | ALA4362185 | ADME | Microsomal stability in human liver microsomes assessed as UGT-mediated metabolism by measuring compound remaining at 5 uM and measured for 60 mins in presence of UDPGA by UPLC-MS/MS analysis (Rvb = 100%) | Homo sapiens | 7 | ALA4359864 | microsome format | Scientific Literature | |
| 11. | ALA4403841 | ADME | Drug metabolism in human liver S9 fractions assessed as assessed as UGT-mediated phase 2 metabolism at 1 mM preincubated for 5 mins followed by NADPH addition and measured after 60 mins by RP-UHPLC-DAD analysis relative to control | Homo sapiens | 2 | ALA4402547 | subcellular format | Scientific Literature | |
| 12. | ALA4415708 | ADME | Drug metabolism in human liver S9 fraction assessed as UGT-mediated metabolism by measuring compound remaining at 5 uM measured immediately in presence of UDPGA by UPLC-MS analysis | Homo sapiens | 1 | ALA4414577 | subcellular format | Scientific Literature | |
| 13. | ALA4415709 | ADME | Drug metabolism in human liver S9 fraction assessed as UGT-mediated metabolism by measuring compound remaining at 5 uM incubated for 15 mins in presence of UDPGA by UPLC-MS analysis | Homo sapiens | 1 | ALA4414577 | subcellular format | Scientific Literature | |
| 14. | ALA4415710 | ADME | Drug metabolism in human liver S9 fraction assessed as UGT-mediated metabolism by measuring compound remaining at 5 uM incubated for 30 mins in presence of UDPGA by UPLC-MS analysis | Homo sapiens | 1 | ALA4414577 | subcellular format | Scientific Literature | |
| 15. | ALA4415711 | ADME | Drug metabolism in human liver S9 fraction assessed as UGT-mediated metabolism by measuring compound remaining at 5 uM incubated for 60 mins in presence of UDPGA by UPLC-MS analysis | Homo sapiens | 1 | ALA4414577 | subcellular format | Scientific Literature | |
| 16. | ALA4424111 | ADME | Drug metabolism in human liver S9 fraction assessed as UGT-mediated metabolism by measuring parent compound remaining at 5 uM measured immediately in presence of UDPGA by UPLC analysis | Homo sapiens | 1 | ALA4422651 | subcellular format | Scientific Literature | |
| 17. | ALA4424112 | ADME | Drug metabolism in human liver S9 fraction assessed as UGT-mediated metabolism by measuring parent compound remaining at 5 uM measured after 15 mins in presence of UDPGA by UPLC analysis | Homo sapiens | 1 | ALA4422651 | subcellular format | Scientific Literature | |
| 18. | ALA4424113 | ADME | Drug metabolism in human liver S9 fraction assessed as UGT-mediated metabolism by measuring parent compound remaining at 5 uM measured after 30 mins in presence of UDPGA by UPLC analysis | Homo sapiens | 1 | ALA4422651 | subcellular format | Scientific Literature | |
| 19. | ALA4424114 | ADME | Drug metabolism in human liver S9 fraction assessed as UGT-mediated metabolism by measuring parent compound remaining at 5 uM measured after 60 mins in presence of UDPGA by UPLC analysis | Homo sapiens | 1 | ALA4422651 | subcellular format | Scientific Literature | |
| 20. | ALA4624406 | ADME | Substrate activity at UDP-glycosyltransferase (unknown origin) assessed as enzyme-mediated metabolite formation in presence of UP-glucose by HPLC-LC/MS analysis | Homo sapiens | 1 | ALA4622896 | protein format | Scientific Literature |
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