| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4309232 | A | Induction of CYP450 (unknown origin) | Homo sapiens | 1 | ALA4308832 | protein format | Scientific Literature | |
| 2. | ALA4312975 | A | Drug metabolism in human liver microsomes assessed as CYP-mediated (1-(4-Methoxybenzyl)pyrrolidine-2,2-diyl)dimethanol formation by UPLC-MS analysis | Homo sapiens | 1 | ALA4311950 | microsome format | Scientific Literature | |
| 3. | ALA4326443 | A | Inhibition of human CYP450 at 25 uM | Homo sapiens | 1 | ALA4325835 | protein format | Scientific Literature | |
| 4. | ALA4331397 | A | Drug metabolism in human liver microsomes assessed as cytochrome P450-mediated 3-(1-(2-methylquinolin-4-yl)vinyl)-9H-carbazole metabolite formation at 100 uM after 6 hrs in presence of NADPH generating system by HPLC-UV-MS analysis | Homo sapiens | 1 | ALA4330077 | microsome format | Scientific Literature | |
| 5. | ALA4331399 | A | Drug metabolism in human liver microsomes assessed as cytochrome P450-mediated 6-(1-(3-hydroxy-4-methoxyphenyl)vinyl)-2,3,4-trimethoxyphenol metabolite formation at 100 uM after 6 hrs in presence of NADPH generating system by HPLC-UV-MS analysis | Homo sapiens | 1 | ALA4330077 | microsome format | Scientific Literature | |
| 6. | ALA4331401 | A | Drug metabolism in human liver microsomes assessed as cytochrome P450-mediated 4-(1-(3-hydroxy-4-methoxyphenyl)vinyl)-2,6-dimethoxyphenol metabolite formation at 100 uM after 6 hrs in presence of NADPH generating system by HPLC-UV-MS analysis | Homo sapiens | 1 | ALA4330077 | microsome format | Scientific Literature | |
| 7. | ALA4331403 | A | Drug metabolism in human liver microsomes assessed as cytochrome P450-mediated 2-methoxy-5-(1-(3,4,5-trimethoxyphenyl)vinyl)cyclohexa-2,5-diene-1,4-dione metabolite formation at 100 uM after 6 hrs in presence of NADPH generating system by HPLC-UV-MS analysis | Homo sapiens | 1 | ALA4330077 | microsome format | Scientific Literature | |
| 8. | ALA4331405 | A | Drug metabolism in human liver microsomes assessed as cytochrome P450-mediated N-demethylated metabolite formation at 100 uM after 6 hrs in presence of NADPH generating system by HPLC-UV-MS analysis | Homo sapiens | 4 | ALA4330077 | microsome format | Scientific Literature | |
| 9. | ALA4331407 | A | Drug metabolism in human liver microsomes assessed as cytochrome P450-mediated hydroxylated metabolite formation at 100 uM after 6 hrs in presence of NADPH generating system by HPLC-UV-MS analysis | Homo sapiens | 4 | ALA4330077 | microsome format | Scientific Literature | |
| 10. | ALA4331411 | A | Drug metabolism in human liver microsomes assessed as cytochrome P450-mediated O-demethylated metabolite formation at 100 uM after 6 hrs in presence of NADPH generating system by HPLC-UV-MS analysis | Homo sapiens | 1 | ALA4330077 | microsome format | Scientific Literature | |
| 11. | ALA4331416 | A | Drug level in human liver microsomes treated with 9-Methyl-3-(1-(2-methylquinolin-4-yl)vinyl)-9H-carbazole assessed as CYP450-mediated compound metabolism at 100 uM after 6 hrs in presence of NADPH generating system by HPLC-UV-MS analysis | Homo sapiens | 1 | ALA4330077 | microsome format | Scientific Literature | |
| 12. | ALA4331418 | A | Drug level in human liver microsomes treated with isocombratestatin-A4 assessed as CYP450-mediated compound metabolism at 100 uM after 6 hrs in presence of NADPH generating system by HPLC-UV-MS analysis | Homo sapiens | 3 | ALA4330077 | microsome format | Scientific Literature | |
| 13. | ALA4333779 | A | Inhibition of human CYP450 | Homo sapiens | 2 | ALA4330138 | protein format | Scientific Literature | |
| 14. | ALA4345275 | A | Inhibition of CYP isoform (unknown origin) | Homo sapiens | 1 | ALA4342490 | protein format | Scientific Literature | |
| 15. | ALA4348890 | A | Inhibition of cytochrome P450 (unknown origin) | Homo sapiens | 1 | ALA4346703 | protein format | Scientific Literature | |
| 16. | ALA4348891 | A | Time dependent inhibition of cytochrome P450 (unknown origin) | Homo sapiens | 1 | ALA4346703 | protein format | Scientific Literature | |
| 17. | ALA4351236 | A | Drug metabolism in human hepatocytes assessed as cytochrome P450-mediated N-demethylated metabolite formation incubated for 120 mins by LC-QTOFMS analysis | Homo sapiens | 1 | ALA4350955 | cell-based format | Scientific Literature | |
| 18. | ALA4351237 | A | Inhibition of CYP450 assessed as maximum reduction in metabolite formation using coumarin based substrate by fluorescence assay | Homo sapiens | 4 | ALA4350955 | protein format | Scientific Literature | |
| 19. | ALA4351265 | A | Drug metabolism in human hepatocytes assessed as cytochrome P450-mediated hydroxylated metabolite formation incubated for 120 mins by LC-QTOFMS analysis | Homo sapiens | 5 | ALA4350955 | cell-based format | Scientific Literature | |
| 20. | ALA4351271 | A | Drug metabolism in human hepatocytes assessed as cytochrome P450-mediated O-glucuronidated metabolite formation incubated for 120 mins by LC-QTOFMS analysis | Homo sapiens | 3 | ALA4350955 | cell-based format | Scientific Literature |
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