# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4257233 | A | Stability of the compound assessed as chymotrypsin (unknown origin)-mediated compound hydrolysis at 250 uM by HPLC analysis | Homo sapiens | 2 | ALA4257221 | assay format | Patent Bioactivity Data | |
2. | ALA4307506 | B | Inhibition of human chymotrypsin using Suc-AAPF-MCA as substrate by fluorescence based assay | Homo sapiens | 3 | ALA4304798 | protein format | Scientific Literature | |
3. | ALA4314204 | B | Inhibition of human chymotrypsin using S-2586 as substrate incubated for 15 mins followed by substrate addition and measured after 1 hr by chromogenic assay | Homo sapiens | 2 | ALA4311982 | protein format | Scientific Literature | |
4. | ALA4320631 | A | Stability of the compound assessed as chymotrypsin (unknown origin)-mediated compound hydrolysis after 8 hrs by SDS-PAGE analysis | Homo sapiens | 2 | ALA4316596 | protein format | Scientific Literature | |
5. | ALA4320632 | A | Stability of the compound assessed as chymotrypsin (unknown origin)-mediated compound hydrolysis after 4 hrs by SDS-PAGE analysis | Homo sapiens | 2 | ALA4316596 | protein format | Scientific Literature | |
6. | ALA4320636 | A | Stability of the compound assessed as chymotrypsin (unknown origin)-mediated compound hydrolysis after 1 hrs by SDS-PAGE analysis | Homo sapiens | 1 | ALA4316596 | protein format | Scientific Literature | |
7. | ALA4320639 | A | Stability of the compound assessed as chymotrypsin (unknown origin)-mediated compound hydrolysis by measuring compound helicity by CD spectroscopy | Homo sapiens | 2 | ALA4316596 | protein format | Scientific Literature | |
8. | ALA4320997 | B | Inhibition of Chymotrypsin (unknown origin) assessed as residual enzyme activity at 10 uM | Homo sapiens | 9 | ALA4316605 | protein format | Scientific Literature | |
9. | ALA4320998 | B | Inhibition of Chymotrypsin (unknown origin) assessed as reduction in enzyme activity | Homo sapiens | 9 | ALA4316605 | protein format | Scientific Literature | |
10. | ALA4357079 | A | Inhibition of human chymotrypsin at 100 uM | Homo sapiens | 1 | ALA4354828 | protein format | Scientific Literature | |
11. | ALA4372625 | A | Substrate activity at chymotrypsin (unknown origin) by Michaelis-Menten plot analysis | Homo sapiens | 2 | ALA4371052 | protein format | Scientific Literature | |
12. | ALA4380413 | B | Inhibition of human chymotrypsin using Suc-AAPF-MCA as substrate at pH 8 and 298 K measured every 60 secs for 600 secs | Homo sapiens | 11 | ALA4376864 | protein format | Scientific Literature | |
13. | ALA4381917 | B | Inhibition of chymotrypsin (unknown origin) assessed as reduction in pNA release using chromogenic Suc-Ala-Ala-Pro-Phe-pNA substrate measured over 12.5 mins by spectrophotometry | Homo sapiens | 3 | ALA4376896 | protein format | Scientific Literature | |
14. | ALA4427817 | B | Inhibition of human chymotrypsin | Homo sapiens | 4 | ALA4425182 | protein format | Scientific Literature | |
15. | ALA4495586 | F | Chymotrypsin inhibition percentage at 10 µM by FRET kind of response from peptide substrate | Homo sapiens | 51 | ALA4495564 | assay format | SARS-CoV-2 Screening Data 2020-21 | |
16. | ALA4617702 | A | Inhibition of mammalian chymotrypsin (unknown origin) using Suc-AAPF-AMC as substrate preincubated for 10 mins followed by substrate addition measured after 30 mins | Homo sapiens | 1 | ALA4616632 | protein format | Scientific Literature | |
17. | ALA4618310 | B | Inhibition of human chymotrypsin by spectrophotometry | Homo sapiens | 1 | ALA4616668 | protein format | Scientific Literature | |
18. | ALA4624593 | B | Inhibition of chymotrypsin (unknown origin) at 10 uM relative to control | Homo sapiens | 1 | ALA4622904 | protein format | Scientific Literature | |
19. | ALA4825429 | B | Inhibition of Chymotrypsin (unknown origin) assessed as residual enzyme activity at 20 uM by FRET assay relative to control | Homo sapiens | 7 | ALA4823320 | protein format | Scientific Literature | |
20. | ALA5032401 | A | Stability of the compound in PBS at pH 7.4 assessed as chymotrypsin (unknown origin)-mediated proteolysis by measuring remaining compound after 12 hrs by HPLC analysis | Homo sapiens | 2 | ALA5030565 | protein format | Scientific Literature |