| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4310934 | B | Inhibition of HDAC class 1 in human A549 cells using histone H4K12 as substrate measured after 4 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA4329591 | B | Inhibition of HDAC class 1 in human HeLa cells after 4 hrs by spectrophotometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4338439 | B | Inhibition of class 1 HDAC in human CAL27 cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring combination index at 3.2 uM in presence of 0.32 uM cisplatin by MTT assay based Chou-Talalay analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA4338459 | B | Inhibition of class 1 HDAC in human CAL27 cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring cisplatin IC50 at 5 uM preincubated for 48 hrs followed by cisplatin addition and measured after 72 hrs by MTT assay (Rvb = 9.79 uM) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4338460 | B | Inhibition of class 1 HDAC in human CAL27 cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring fold reduction in cisplatin IC50 at 5 uM preincubated for 48 hrs followed by cisplatin addition and measured after 72 hrs by MTT assay relative to cisplatin IC50 | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4338461 | B | Inhibition of class 1 HDAC in human CAL27 cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring fold reduction in cisplatin IC50 at 0.5 uM preincubated for 48 hrs followed by cisplatin addition and measured after 72 hrs by MTT assay relative to cisplatin IC50 | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA4338462 | B | Inhibition of class 1 HDAC in human CAL27 cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring fold reduction in cisplatin IC50 at 3.2 uM preincubated for 48 hrs followed by cisplatin addition and measured after 72 hrs by MTT assay relative to cisplatin IC50 | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4338463 | B | Inhibition of class 1 HDAC in human Cal27CisR cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring cisplatin IC50 at 5 uM preincubated for 48 hrs followed by cisplatin addition and measured after 72 hrs by MTT assay (Rvb = 63.2 uM) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4338464 | B | Inhibition of class 1 HDAC in human Cal27CisR cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring fold reduction in cisplatin IC50 at 5 uM preincubated for 48 hrs followed by cisplatin addition and measured after 72 hrs by MTT assay relative to cisplatin IC50 | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4338465 | B | Inhibition of class 1 HDAC in human Cal27CisR cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring fold reduction in cisplatin IC50 at 0.5 uM preincubated for 48 hrs followed by cisplatin addition and measured after 72 hrs by MTT assay relative to cisplatin IC50 | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA4338466 | B | Inhibition of class 1 HDAC in human Cal27CisR cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring fold reduction in cisplatin IC50 at 3.2 uM preincubated for 48 hrs followed by cisplatin addition and measured after 72 hrs by MTT assay relative to cisplatin IC50 | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4338467 | B | Inhibition of class 1 HDAC in human CAL27 cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring combination index at 0.25 uM in presence of 1 uM cisplatin by MTT assay based Chou-Talalay analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4338468 | B | Inhibition of class 1 HDAC in human CAL27 cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring combination index at 0.25 uM in presence of 0.32 uM cisplatin by MTT assay based Chou-Talalay analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4338469 | B | Inhibition of class 1 HDAC in human CAL27 cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring combination index at 0.25 uM in presence of 0.1 uM cisplatin by MTT assay based Chou-Talalay analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4338470 | B | Inhibition of class 1 HDAC in human CAL27 cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring combination index at 0.1 uM in presence of 10 uM cisplatin by MTT assay based Chou-Talalay analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4338471 | B | Inhibition of class 1 HDAC in human CAL27 cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring combination index at 0.1 uM in presence of 3.2 uM cisplatin by MTT assay based Chou-Talalay analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4338472 | B | Inhibition of class 1 HDAC in human CAL27 cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring combination index at 0.1 uM in presence of 1 uM cisplatin by MTT assay based Chou-Talalay analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4338473 | B | Inhibition of class 1 HDAC in human CAL27 cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring combination index at 0.1 uM in presence of 0.32 uM cisplatin by MTT assay based Chou-Talalay analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4338474 | B | Inhibition of class 1 HDAC in human CAL27 cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring combination index at 0.1 uM in presence of 0.1 uM cisplatin by MTT assay based Chou-Talalay analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4338475 | B | Inhibition of class 1 HDAC in human CAL27 cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring combination index at 5 uM in presence of 10 uM cisplatin by MTT assay based Chou-Talalay analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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