| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5253843 | B | Inhibition of mTORC2 in human MDA-MB-231 cells assessed as reduction in Akt phosphorylation at Ser473 residue at 15 to 25 uM by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA5253844 | B | Inhibition of mTORC2 in human MCF7 cells assessed as reduction in Akt phosphorylation at Ser473 residue at 15 to 25 uM by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA5253851 | B | Inhibition of mTORC2 in human MCF7 cells assessed as reduction in Akt phosphorylation at Ser473 residue at 0.25 to 0.5 uM by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA5253852 | B | Inhibition of mTORC2 in human MDA-MB-231 cells assessed as reduction in Akt phosphorylation at Ser473 residue at 0.25 to 0.5 uM by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4308949 | B | Inhibition of recombinant mTORC2 (unknown origin) expressed in Escherichia coli after 15 mins in presence of gamma-[32]P-ATP by high-throughput screening assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 6. | ALA4308964 | B | Inhibition of mTORC2 (unknown origin) | Homo sapiens | 5 | protein complex format | Scientific Literature | ||
| 7. | ALA4308966 | B | Inhibition of N-terminally FLAG-tagged mTORC2 (unknown origin) expressed in human HeLa cells using S6K1 or Akt1 as substrate after 20 mins by immunoblotting assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA4308973 | B | Inhibition of mTORC2 in HEK293 cells using GST-tagged S6K1 or Akt1 as substrate after 30 mins by immunoblotting assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4322495 | B | Inhibition of mTORC2 in human A2058 cells assessed as reduction in PKB phosphorylation at S473 residues incubated for 1 hr by Western blot analysis | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
| 10. | ALA4352823 | B | Inhibition of mTORC2 in human RD cells assessed as reduction in Akt phosphorylation at Ser473 site at 20 uM incubated for 2 hrs in presence of insulin by Western blot analysis | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
| 11. | ALA4370820 | B | Inhibition of mTORC2 signaling in human HEK293 cells assessed as reduction in leucine-induced AKT phosphorylation at 200 uM preincubated for 50 mins followed by leucine-stimulation and measured after 10 mins by Western blot analysis | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 12. | ALA4410951 | B | Inhibition of mTORC2 in human A431 cells assessed as AKT phosphorylation at S473 residue incubated for 3 hrs by HTRF assay | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
| 13. | ALA4432844 | B | Inhibition of mTORC2 in HEK293T/17 cells assessed as reduction in Akt phosphorylation at Ser-473 residue after 2 hrs by sandwich immunoassay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4668257 | B | Inhibition of mTORC2 in human A2058 cells assessed as reduction in PKB phosphorylation at S473 residue incubated for 1 hr by Western blot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 15. | ALA5127283 | B | Inhibition of mTORC2 (unknown origin) | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 16. | ALA5216191 | B | Inhibition of mTORC2 (unknown origin) | Homo sapiens | 19 | protein complex format | Scientific Literature | ||
| 17. | ALA5216193 | B | Inhibition of mTORC2 in human PC-3 cells assessed as measuring phosphorylated Akt level incubated for 24 hrs by AlphaLISA assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 18. | ALA5216212 | B | Inhibition of mTORC2 (unknown origin) assessed as measuring phosphorylated AKT at 0.5 uM relative to control | Homo sapiens | 3 | protein complex format | Scientific Literature | ||
| 19. | ALA5216216 | B | Inhibition of mTORC2 in human A-431 cells assessed as phosphorylated AKT level incubated for 3 hrs by HTRF assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 20. | ALA5216223 | B | Inhibition of mTORC2 in human MCF7 cells assessed as measuring phosphorylated AKT incubated for 2 hrs by AlphaLISA assay | Homo sapiens | 15 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!