# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA682848 | F | Inhibition of src kinase activity in Src transformed rat fibroblasts | Rattus norvegicus | 12 | ALA1135352 | assay format | Scientific Literature | |
2. | ALA843326 | B | Inhibition of v-Src tyrosine kinase autophosphorylation in SR3Y1 cells after 15 hr exposure | 20 | ALA1145797 | cell-based format | Scientific Literature | ||
3. | ALA843327 | F | Inhibition of v-Src tyrosine kinase autophosphorylation in SR3Y1 cells after 15 hr | Rattus norvegicus | 1 | ALA1145797 | cell-based format | Scientific Literature | |
4. | ALA844132 | F | Inhibition of v-Src tyrosine kinase autophosphorylation in SR3Y1 cells after 15 hr (not tested) | Rattus norvegicus | 3 | ALA1145797 | cell-based format | Scientific Literature | |
5. | ALA885860 | B | Inhibition of Src in rat fibroblasts | Rattus norvegicus | 11 | ALA1139073 | assay format | Scientific Literature | |
6. | ALA3861109 | B | Inhibition of Src in Sprague-Dawley rat primary mixed mesecephalic neuron/glial cells assessed as suppression of LPS-induced IL-1beta expression at 10 uM preincubated for 1 hr followed by LPS challenge measured after 5 hrs by ELISA | Rattus norvegicus | 4 | ALA3860061 | assay format | Scientific Literature | |
7. | ALA3861110 | B | Inhibition of Src in Sprague-Dawley rat primary mixed mesecephalic neuron/glial cells assessed as suppression of LPS-induced TNFalpha expression at 10 uM preincubated for 1 hr followed by LPS challenge measured after 5 hrs by ELISA | Rattus norvegicus | 4 | ALA3860061 | assay format | Scientific Literature | |
8. | ALA3861111 | B | Inhibition of SRC in Sprague-Dawley rat primary mixed mesecephalic neuron/glial cells assessed as protection against LPS-induced dopaminergic neuro-toxicity by measuring TH expression at 10 uM preincubated for 1 hr followed by LPS challenge measured after 7 days by Western blot analysis | Rattus norvegicus | 4 | ALA3860061 | assay format | Scientific Literature | |
9. | ALA3861148 | B | Inhibition of Src in Sprague-Dawley rat primary microglia cells assessed as suppression of LPS-stimulated PTEN phosphorylation at Tyr-240 residue at 10 uM preincubated for 1 hr followed by LPS challenge measured after 3 hrs by Western blot analysis | Rattus norvegicus | 1 | ALA3860061 | assay format | Scientific Literature | |
10. | ALA3861149 | B | Inhibition of Src in Sprague-Dawley rat primary microglia cells assessed as suppression of LPS-stimulated Akt phosphorylation at Ser-473 residue at 10 uM preincubated for 1 hr followed by LPS challenge measured after 3 hrs by Western blot analysis | Rattus norvegicus | 1 | ALA3860061 | assay format | Scientific Literature | |
11. | ALA3861150 | B | Inhibition of LPS-induced Src phosphorylation at Tyr-416 residue in Sprague-Dawley rat primary microglia cells at 10 uM preincubated for 1 hr followed by LPS stimulation measured after 3 hrs by Western blot analysis | Rattus norvegicus | 1 | ALA3860061 | assay format | Scientific Literature | |
12. | ALA3861158 | B | Inhibition of Src in Sprague-Dawley rat primary mixed mesecephalic neuron/glial cells assessed as suppression of LPS-induced microglia activation by measuring Iba-1 expression at 10 uM preincubated for 1 hr followed by LPS challenge measured after 5 hrs by ELISA | Rattus norvegicus | 4 | ALA3860061 | assay format | Scientific Literature | |
13. | ALA4839498 | B | Inhibition of Src phosphorylation in rat RBL-2H3 cells assessed as inhibition of Fc epsilonRI-mediated signal transduction by Western blot analysis | Rattus norvegicus | 1 | ALA4837249 | cell-based format | Scientific Literature |