| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2049388 | F | Induction of morphological changes in human WM164 cells assessed as less density and round shape phenotype with fewer dendrites of cells at IC50 after 24 to 48 hrs | Homo sapiens | 1 | ALA2046340 | cell-based format | Scientific Literature | |
| 2. | ALA2049398 | F | Induction of apoptosis in human WM164 cells assessed as less accumulation at sub-G1 phase at IC50 after 24 by caspase-glo 3/7 assay | Homo sapiens | 1 | ALA2046340 | cell-based format | Scientific Literature | |
| 3. | ALA4198047 | F | Growth inhibition of human WM164 cells after 72 hrs by MTS assay | Homo sapiens | 35 | ALA4196060 | assay format | Scientific Literature | |
| 4. | ALA4366986 | F | Antiproliferative activity against human WM164 cells after 72 hrs by MTT assay | Homo sapiens | 28 | ALA4364286 | cell-based format | Scientific Literature | |
| 5. | ALA4604346 | F | Cytotoxicity against human WM164 cells harboring BRAF V600E mutant assessed as reduction in cell viability after 24 hrs by EZ4U reagent based spectrophotometric method | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 6. | ALA4604347 | F | Cytotoxicity against human WM164 cells harboring BRAF V600E mutant assessed as reduction in cell viability after 48 hrs by EZ4U reagent based spectrophotometric method | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 7. | ALA4604348 | F | Cytotoxicity against human WM164 cells harboring BRAF V600E mutant assessed as reduction in cell viability after 72 hrs by EZ4U reagent based spectrophotometric method | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 8. | ALA4604367 | F | Induction of apoptosis in human WM164 cells assessed as viable cells at IC50 concentration after 6 hrs by Annexin V/SYTOX Green based flow cytometric analysis (Rvb = 94.77%) | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 9. | ALA4604368 | F | Induction of apoptosis in human WM164 cells assessed as early apoptotic cells at IC50 concentration after 6 hrs by Annexin V/SYTOX Green based flow cytometric analysis (Rvb = 3.01%) | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 10. | ALA4604369 | F | Induction of apoptosis in human WM164 cells assessed as late apoptotic cells at IC50 concentration after 6 hrs by Annexin V/SYTOX Green based flow cytometric analysis (Rvb = 1.41%) | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 11. | ALA4604370 | F | Induction of apoptosis in human WM164 cells assessed as necrotic cells at IC50 concentration after 6 hrs by Annexin V/SYTOX Green based flow cytometric analysis (Rvb = 0.81%) | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 12. | ALA4604387 | F | Induction of apoptosis in human WM164 cells assessed as viable cells at IC50 concentration after 24 hrs by Annexin V/SYTOX Green based flow cytometric analysis (Rvb = 94.62%) | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 13. | ALA4604388 | F | Induction of apoptosis in human WM164 cells assessed as early apoptotic cells at IC50 concentration after 24 hrs by Annexin V/SYTOX Green based flow cytometric analysis (Rvb = 2.72%) | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 14. | ALA4604389 | F | Induction of apoptosis in human WM164 cells assessed as late apoptotic cells at IC50 concentration after 24 hrs by Annexin V/SYTOX Green based flow cytometric analysis (Rvb = 1.81%) | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 15. | ALA4604390 | F | Induction of apoptosis in human WM164 cells assessed as necrotic cells at IC50 concentration after 24 hrs by Annexin V/SYTOX Green based flow cytometric analysis (Rvb = 0.85%) | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 16. | ALA4604398 | F | Cytotoxicity against human WM164 cells harboring BRAF V600E mutant assessed as reduction in cell viability by EZ4U reagent based spectrophotometric method | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 17. | ALA4604407 | F | Induction of apoptosis in human WM164 cells assessed as increase in caspase -3 activity at IC50 concentration after 24 hrs by Alexa Fluor 647 antibody based flow cytometric analysis | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 18. | ALA4604412 | F | Induction of apoptosis in human WM164 cells assessed as up regulation of PMAIP1 at IC50 concentration after 24 hrs by mRNA sequencing method relative to control | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 19. | ALA4604415 | F | Antitumour activity against human WM164 cells xenografted in NU(NCr)-Foxn1 mouse assessed as increase in necrotic cells at 1 to 4 ug/g administered for three consecutive days with 1 day interval for four cycle by hematoxylin and eosin staining based microscopic analysis | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 20. | ALA4604417 | F | Antitumour activity against human WM164 cells xenografted in NU(NCr)-Foxn1 mouse assessed as increase in caspase -activity at 1 to 4 ug/g administered for three consecutive days with 1 day interval for four cycle by hematoxylin and eosin staining based microscopic analysis | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature |
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