| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1219701 | F | Induction of apoptosis in human WM793 cells assessed as reduction in mitochondrial polarization upto 4 ug/ml by flow cytometry | Homo sapiens | 8 | ALA1212901 | cell-based format | Scientific Literature | |
| 2. | ALA1219702 | F | Induction of apoptosis in human WM793 cells assessed as vacuolization upto 4 ug/ml by flow cytometry | Homo sapiens | 1 | ALA1212901 | cell-based format | Scientific Literature | |
| 3. | ALA1219704 | F | Induction of apoptosis in human WM793 cells assessed as mitochondrial fragmentation upto 4 ug/ml by flow cytometry | Homo sapiens | 5 | ALA1212901 | cell-based format | Scientific Literature | |
| 4. | ALA1219706 | F | Induction of apoptosis in human WM793 cells assessed as change in fluorescence intensity using TMRM labeling by flow cytometry | Homo sapiens | 11 | ALA1212901 | cell-based format | Scientific Literature | |
| 5. | ALA4604349 | F | Cytotoxicity against human WM793 cells harboring BRAF V600E mutant assessed as reduction in cell viability after 24 hrs by EZ4U reagent based spectrophotometric method | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 6. | ALA4604350 | F | Cytotoxicity against human WM793 cells harboring BRAF V600E mutant assessed as reduction in cell viability after 48 hrs by EZ4U reagent based spectrophotometric method | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 7. | ALA4604351 | F | Cytotoxicity against human WM793 cells harboring BRAF V600E mutant assessed as reduction in cell viability after 72 hrs by EZ4U reagent based spectrophotometric method | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 8. | ALA4604371 | F | Induction of apoptosis in human WM793 cells assessed as viable cells at IC50 concentration after 6 hrs by Annexin V/SYTOX Green based flow cytometric analysis (Rvb = 96.2%) | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 9. | ALA4604372 | F | Induction of apoptosis in human WM793 cells assessed as early apoptotic cells at IC50 concentration after 6 hrs by Annexin V/SYTOX Green based flow cytometric analysis (Rvb = 2.77%) | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 10. | ALA4604373 | F | Induction of apoptosis in human WM793 cells assessed as late apoptotic cells at IC50 concentration after 6 hrs by Annexin V/SYTOX Green based flow cytometric analysis (Rvb = 0.71%) | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 11. | ALA4604374 | F | Induction of apoptosis in human WM793 cells assessed as necrotic cells at IC50 concentration after 6 hrs by Annexin V/SYTOX Green based flow cytometric analysis (Rvb = 0.32%) | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 12. | ALA4604391 | F | Induction of apoptosis in human WM793 cells assessed as viable cells at IC50 concentration after 24 hrs by Annexin V/SYTOX Green based flow cytometric analysis (Rvb = 96.52%) | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 13. | ALA4604392 | F | Induction of apoptosis in human WM793 cells assessed as early apoptotic cells at IC50 concentration after 24 hrs by Annexin V/SYTOX Green based flow cytometric analysis (Rvb = 2.64%) | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 14. | ALA4604393 | F | Induction of apoptosis in human WM793 cells assessed as late apoptotic cells at IC50 concentration after 24 hrs by Annexin V/SYTOX Green based flow cytometric analysis (Rvb = 0.66%) | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 15. | ALA4604394 | F | Induction of apoptosis in human WM793 cells assessed as necrotic cells at IC50 concentration after 24 hrs by Annexin V/SYTOX Green based flow cytometric analysis (Rvb = 0.17%) | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 16. | ALA4604399 | F | Cytotoxicity against human WM793 cells harboring BRAF V600E mutant assessed as reduction in cell viability by EZ4U reagent based spectrophotometric method | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 17. | ALA4604408 | F | Induction of apoptosis in human WM793 cells assessed as increase in caspase -3 activity at IC50 concentration after 24 hrs by Alexa Fluor 647 antibody based flow cytometric analysis | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 18. | ALA4604419 | F | Induction of apoptosis in human WM793 cells assessed as up regulation of NOXA protein expression at IC50 concentration after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 19. | ALA4604424 | F | Induction of apoptosis in human WM793 cells assessed as effect on BAX mRNA expression at IC50 concentration after 6 to 24 hrs by RT-qPCR analysis | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 20. | ALA4604425 | F | Induction of apoptosis in human WM793 cells assessed as effect on BAD mRNA expression at IC50 concentration after 6 to 24 hrs by RT-qPCR analysis | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature |
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