| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4604340 | F | Cytotoxicity against human MUGMel2 cells harboring NRAS pQ61K mutant assessed as reduction in cell viability after 24 hrs by EZ4U reagent based spectrophotometric method | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 2. | ALA4604341 | F | Cytotoxicity against human MUGMel2 cells harboring NRAS pQ61K mutant assessed as reduction in cell viability after 48 hrs by EZ4U reagent based spectrophotometric method | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 3. | ALA4604342 | F | Cytotoxicity against human MUGMel2 cells harboring NRAS pQ61K mutant assessed as reduction in cell viability after 72 hrs by EZ4U reagent based spectrophotometric method | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 4. | ALA4604359 | F | Induction of apoptosis in human MUGMel2 cells assessed as viable cells at IC50 concentration after 6 hrs by Annexin V/SYTOX Green based flow cytometric analysis (Rvb = 91.12%) | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 5. | ALA4604360 | F | Induction of apoptosis in human MUGMel2 cells assessed as early apoptotic cells at IC50 concentration after 6 hrs by Annexin V/SYTOX Green based flow cytometric analysis (Rvb = 2.89%) | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 6. | ALA4604361 | F | Induction of apoptosis in human MUGMel2 cells assessed as late apoptotic cells at IC50 concentration after 6 hrs by Annexin V/SYTOX Green based flow cytometric analysis (Rvb = 5.69%) | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 7. | ALA4604362 | F | Induction of apoptosis in human MUGMel2 cells assessed as necrotic cells at IC50 concentration after 6 hrs by Annexin V/SYTOX Green based flow cytometric analysis (Rvb = 0.3%) | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 8. | ALA4604379 | F | Induction of apoptosis in human MUGMel2 cells assessed as viable cells at IC50 concentration after 24 hrs by Annexin V/SYTOX Green based flow cytometric analysis (Rvb = 85.95%) | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 9. | ALA4604380 | F | Induction of apoptosis in human MUGMel2 cells assessed as early apoptotic cells at IC50 concentration after 24 hrs by Annexin V/SYTOX Green based flow cytometric analysis (Rvb = 3.31%) | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 10. | ALA4604381 | F | Induction of apoptosis in human MUGMel2 cells assessed as late apoptotic cells at IC50 concentration after 24 hrs by Annexin V/SYTOX Green based flow cytometric analysis (Rvb = 9.64%) | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 11. | ALA4604382 | F | Induction of apoptosis in human MUGMel2 cells assessed as necrotic cells at IC50 concentration after 24 hrs by Annexin V/SYTOX Green based flow cytometric analysis (Rvb = 1.1%) | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 12. | ALA4604396 | F | Cytotoxicity against human MUGMel2 cells harboring NRAS pQ61K mutant assessed as reduction in cell viability by EZ4U reagent based spectrophotometric method | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 13. | ALA4604405 | F | Induction of apoptosis in human MUGMel2 cells assessed as increase in caspase -3 activity at IC50 concentration after 24 hrs by Alexa Fluor 647 antibody based flow cytometric analysis | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 14. | ALA4604422 | F | Induction of apoptosis in human MUGMel2 cells assessed as up regulation of NOXA protein expression at IC50 concentration after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 15. | ALA4604430 | F | Induction of apoptosis in human MUGMel2 cells assessed as effect on BAX mRNA expression at IC50 concentration after 6 to 24 hrs by RT-qPCR analysis | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 16. | ALA4604431 | F | Induction of apoptosis in human MUGMel2 cells assessed as effect on BAD mRNA expression at IC50 concentration after 6 to 24 hrs by RT-qPCR analysis | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 17. | ALA4604440 | F | Induction of apoptosis in human MUGMel2 cells assessed as up regulation of NOXA at IC50 concentration after 6 to 24 hrs by RT-qPCR analysis relative to control | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 18. | ALA4604454 | F | Induction of apoptosis in human MUGMel2 cells assessed as effect on PUMA protein expression at IC50 concentration after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 19. | ALA4604455 | F | Induction of apoptosis in human MUGMel2 cells assessed as effect on BAX protein expression at IC50 concentration after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
| 20. | ALA4604456 | F | Induction of apoptosis in human MUGMel2 cells assessed as effect on BAD protein expression at IC50 concentration after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature |
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