# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4604337 | F | Cytotoxicity against human MUGMel1 cells assessed as reduction in cell viability after 24 hrs by EZ4U reagent based spectrophotometric method | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
2. | ALA4604338 | F | Cytotoxicity against human MUGMel1 cells assessed as reduction in cell viability after 48 hrs by EZ4U reagent based spectrophotometric method | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
3. | ALA4604339 | F | Cytotoxicity against human MUGMel1 cells assessed as reduction in cell viability after 72 hrs by EZ4U reagent based spectrophotometric method | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
4. | ALA4604355 | F | Induction of apoptosis in human MUGMel1 cells assessed as viable cells at IC50 concentration after 6 hrs by Annexin V/SYTOX Green based flow cytometric analysis (Rvb = 96.01%) | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
5. | ALA4604356 | F | Induction of apoptosis in human MUGMel1 cells assessed as early apoptotic cells at IC50 concentration after 6 hrs by Annexin V/SYTOX Green based flow cytometric analysis (Rvb = 2.55%) | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
6. | ALA4604357 | F | Induction of apoptosis in human MUGMel1 cells assessed as late apoptotic cells at IC50 concentration after 6 hrs by Annexin V/SYTOX Green based flow cytometric analysis (Rvb = 1.04%) | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
7. | ALA4604358 | F | Induction of apoptosis in human MUGMel1 cells assessed as necrotic cells at IC50 concentration after 6 hrs by Annexin V/SYTOX Green based flow cytometric analysis (Rvb = 0.39%) | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
8. | ALA4604375 | F | Induction of apoptosis in human MUGMel1 cells assessed as viable cells at IC50 concentration after 24 hrs by Annexin V/SYTOX Green based flow cytometric analysis (Rvb = 95.13%) | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
9. | ALA4604376 | F | Induction of apoptosis in human MUGMel1 cells assessed as early apoptotic cells at IC50 concentration after 24 hrs by Annexin V/SYTOX Green based flow cytometric analysis (Rvb = 3.27%) | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
10. | ALA4604377 | F | Induction of apoptosis in human MUGMel1 cells assessed as late apoptotic cells at IC50 concentration after 24 hrs by Annexin V/SYTOX Green based flow cytometric analysis (Rvb = 1.18%) | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
11. | ALA4604378 | F | Induction of apoptosis in human MUGMel1 cells assessed as necrotic cells at IC50 concentration after 24 hrs by Annexin V/SYTOX Green based flow cytometric analysis (Rvb = 0.42%) | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
12. | ALA4604395 | F | Cytotoxicity against human MUGMel1 cells assessed as reduction in cell viability by EZ4U reagent based spectrophotometric method | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
13. | ALA4604404 | F | Induction of apoptosis in human MUGMel1 cells assessed as increase in caspase -3 activity at IC50 concentration after 24 hrs by Alexa Fluor 647 antibody based flow cytometric analysis | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
14. | ALA4604409 | F | Induction of apoptosis in human MUGMel1 cells assessed as increase in caspase -3 activity at IC50 concentration after 24 hrs in presence of caspase -inhibitor by Alexa Fluor 647 antibody based flow cytometric analysis | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
15. | ALA4604410 | F | Induction of cell cycle arrest in human MUGMel1 cells assessed as increase in S phase at IC50 concentration after 24 to 48 hrs by propidium iodide staining based flow cytometric analysis | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
16. | ALA4604413 | F | Induction of apoptosis in human MUGMel1 cells assessed as up regulation of NOXA at IC50 concentration after 6 to 24 hrs by RT-qPCR analysis relative to control | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
17. | ALA4604423 | F | Induction of apoptosis in human MUGMel1 cells assessed as up regulation of NOXA protein expression at IC50 concentration after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
18. | ALA4604432 | F | Induction of apoptosis in human MUGMel1 cells assessed as effect on BAX mRNA expression at IC50 concentration after 6 to 24 hrs by RT-qPCR analysis | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
19. | ALA4604433 | F | Induction of apoptosis in human MUGMel1 cells assessed as effect on BAD mRNA expression at IC50 concentration after 6 to 24 hrs by RT-qPCR analysis | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature | |
20. | ALA4604435 | F | Induction of apoptosis in human MUGMel1 cells assessed as up regulation of PUMA at IC50 concentration after 6 to 24 hrs by RT-qPCR analysis | Homo sapiens | 1 | ALA4602659 | cell-based format | Scientific Literature |