| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4354714 | A | Cytotoxicity against human S1-M1-80 cells assessed as inhibition of cell viability at 5 to 25 uM incubated for 2 hrs by MTT assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA4629381 | F | Potentiation of topotecan-induced apoptosis in human S1-M1-80 cells harboring ABCG2 (unknown origin) assessed as necrotic cells at 10 uM incubated for 48 hrs by annexin V/propidium iodide staining based flow cytometry (Rvb = 0.4%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4629382 | F | Potentiation of topotecan-induced apoptosis in human S1-M1-80 cells harboring ABCG2 (unknown origin) assessed as late apoptotic cells at 10 uM incubated for 48 hrs by annexin V/propidium iodide staining based flow cytometry (Rvb = 6%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4629383 | F | Potentiation of topotecan-induced apoptosis in human S1-M1-80 cells harboring ABCG2 (unknown origin) assessed as early apoptotic cells at 10 uM incubated for 48 hrs by annexin V/propidium iodide staining based flow cytometry (Rvb = 3%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4629384 | F | Potentiation of topotecan-induced apoptosis in human S1-M1-80 cells harboring ABCG2 (unknown origin) assessed as viable cells at 10 uM incubated for 48 hrs by annexin V/propidium iodide staining based flow cytometry (Rvb = 90.6%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4629385 | F | Induction of apoptosis in human S1-M1-80 cells harboring ABCG2 (unknown origin) assessed as necrotic cells at 10 uM incubated for 48 hrs by annexin V/propidium iodide staining based flow cytometry (Rvb = 0.3%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4629386 | F | Induction of apoptosis in human S1-M1-80 cells harboring ABCG2 (unknown origin) assessed as late apoptotic cells at 10 uM incubated for 48 hrs by annexin V/propidium iodide staining based flow cytometry (Rvb = 2.9%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4629387 | F | Induction of apoptosis in human S1-M1-80 cells harboring ABCG2 (unknown origin) assessed as early apoptotic cells at 10 uM incubated for 48 hrs by annexin V/propidium iodide staining based flow cytometry (Rvb = 2.8%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4629388 | F | Induction of apoptosis in human S1-M1-80 cells harboring ABCG2 (unknown origin) assessed as viable cells at 10 uM incubated for 48 hrs by annexin V/propidium iodide staining based flow cytometry (Rvb = 93.9%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4629405 | F | Downregulation of ABCG2 expression in human S1-M1-80 cells at 0.5 to 3 uM incubated for 72 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4629420 | F | Cytotoxicity against human S1-M1-80 cells harboring ABCG2 (unknown origin) after 72 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA5216507 | F | Cytotoxicity against human S1M180 cells in presence of topotecan | Homo sapiens | 1 | cell-based format | Scientific Literature |
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