| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4605875 | B | Protac activity at VHL/HDAC6 in human MM1S cells assessed as HDAC6 degradation at 100 nM measured after 6 hrs by ELISA | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 2. | ALA4605876 | B | Protac activity at VHL/HDAC6 in human MM1S cells assessed as HDAC6 degradation at 100 nM measured after 6 hrs by Western blot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 3. | ALA4605877 | B | Protac activity at VHL/HDAC6 in human MM1S cells assessed as increase in tubulin acetylation at 100 nM measured after 6 hrs by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 4. | ALA4605879 | B | Protac activity at VHL/HDAC6 in human MM1S cells measured after 6 hrs by ELISA | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA4605881 | B | Protac activity at VHL/HDAC6 in human MM1S cells measured after 6 hrs by ELISA relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA4605882 | B | Protac activity at VHL/HDAC6 in human MM1S cells assessed as HDAC6 degradation at 10 nM measured after 4 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4605883 | B | Protac activity at VHL/HDAC6 in human MM1S cells assessed as HDAC6 degradation at 100 nM measured after 4 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4605884 | B | Protac activity at VHL/HDAC6 in human MM1S cells assessed as compound-VHL complex formation at 3 uM after 6 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4605885 | B | Protac activity at VHL/HDAC6 in human MM1S cells assessed as compound-HDAC6 complex formation at 3 uM after 6 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4605886 | B | Protac activity at VHL/HDAC6 in human MM1S cells assessed as induction of tubulin acetylation after 4 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4605887 | B | Protac activity at VHL/HDAC6 in human MM1S cells assessed as induction of tubulin acetylation at 1 uM after 4 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4605888 | B | Protac activity at VHL/HDAC6 in human MM1S cells assessed as increase in tubulin acetylation at 300 nM after 4 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4605898 | B | Protac activity at VHL/HDAC6 in human MM1S cells assessed as tubulin acetylation at 100 nM to 1 microM after 6 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4605899 | B | Protac activity at VHL/HDAC6 in human MM1S cells assessed as reduction in protein level at 100 nM after 30 mins by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4605901 | B | Protac activity at VHL/HDAC6 in human MM1S cells assessed as reduction in protein level at 100 nM after 4 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4605903 | B | Protac activity at VHL/HDAC6 in human MM1S cells assessed as HDAC6 degradation at 100 nM pretreated for 1 hr in presence of proteasome inhibitor MG132 by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4605904 | B | Protac activity at VHL/HDAC6 in human MM1S cells assessed as HDAC6 degradation at 100 nM pretreated for 1 hr in presence of proteasome inhibitor Bortezomib by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4605905 | B | Protac activity at VHL/HDAC6 in human MM1S cells assessed as HDAC6 degradation at 100 nM pretreated for 1 hr in presence of HDAC6 inhibitor Next-A by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4605906 | B | Protac activity at VHL/HDAC6 in human MM1S cells assessed as HDAC6 degradation at 100 nM pretreated for 1 hr in presence of 5 uM VHL-1 by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4605907 | B | Protac activity at VHL/HDAC6 in human HEK293T cells assessed as induction of HDAC degradation by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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