# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4605891 | Binding | Protac activity at VHL/HDAC3 in human MM1S cells assessed as HDAC3 degradation at 100 nM after 4 hrs by Western blot analysis | Homo sapiens | 1 | ALA4602716 | cell-based format | Scientific Literature | |
2. | ALA5045986 | Binding | Protac activity at VHL/HDAC3 in human HCT-116 cells assessed as induction of HDAC3 degradation at 10 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 2 | ALA5042553 | cell-based format | Scientific Literature | |
3. | ALA5045989 | Binding | Protac activity at VHL/HDAC3 in human HCT-116 cells assessed as induction of HDAC3 degradation at 1 to 10 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 9 | ALA5042553 | cell-based format | Scientific Literature | |
4. | ALA5045991 | Binding | Protac activity at VHL/HDAC3 in human HCT-116 cells assessed as induction of HDAC3 degradation at 1 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 5 | ALA5042553 | cell-based format | Scientific Literature | |
5. | ALA5045995 | Binding | Protac activity at VHL/HDAC3 in human HCT-116 cells assessed as induction of HDAC3 degradation at 1 uM incubated for 24 hrs by Western blot analysis relative to control | Homo sapiens | 4 | ALA5042553 | cell-based format | Scientific Literature | |
6. | ALA5045997 | Binding | Protac activity at VHL/HDAC3 in human HCT-116 cells assessed as induction of HDAC3 degradation incubated for 24 hrs by Western blot analysis | Homo sapiens | 4 | ALA5042553 | cell-based format | Scientific Literature | |
7. | ALA5046002 | Binding | Protac activity at VHL/HDAC3 in human HCT-116 cells assessed as increase in H3K56ac levels at 10 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 19 | ALA5042553 | cell-based format | Scientific Literature | |
8. | ALA5046007 | Binding | Protac activity at VHL/HDAC3 in human HCT-116 cells assessed as induction of HDAC3 degradation at 10 uM measured upto 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA5042553 | cell-based format | Scientific Literature | |
9. | ALA5046012 | Binding | Protac activity at VHL/HDAC3 in human HCT-116 cells assessed as induction of HDAC3 degradation at 1 uM measured after 4 hrs by Western blot analysis | Homo sapiens | 1 | ALA5042553 | cell-based format | Scientific Literature | |
10. | ALA5046013 | Binding | Protac activity at VHL/HDAC3 in human HCT-116 cells assessed as induction of HDAC3 degradation at 1 uM measured after 15 hrs by Western blot analysis | Homo sapiens | 1 | ALA5042553 | cell-based format | Scientific Literature | |
11. | ALA5046014 | Binding | Protac activity at VHL/HDAC3 in human HCT-116 cells assessed as induction of HDAC3 degradation at 10 uM measured after 36 to 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA5042553 | cell-based format | Scientific Literature | |
12. | ALA5107738 | Binding | PROTAC activity at VHL/HDAC3 in human HCT-116 cells assessed as induction of HDAC3 degradation at 10 uM incubated for 24 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA5104222 | cell-based format | Scientific Literature | |
13. | ALA5107739 | Binding | PROTAC activity at VHL/HDAC3 in human HCT-116 cells assessed as induction of HDAC3 degradation at 0.1 to 10 uM incubated for 24 hrs by Western blot analysis relative to control | Homo sapiens | 3 | ALA5104222 | cell-based format | Scientific Literature | |
14. | ALA5107740 | Binding | PROTAC activity at VHL/HDAC3 in human HCT-116 cells assessed as induction of HDAC3 degradation at 1 uM incubated for 24 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA5104222 | cell-based format | Scientific Literature | |
15. | ALA5107744 | Binding | PROTAC activity at VHL/HDAC3 in human HCT-116 cells assessed as induction of HDAC1 degradation incubated for 24 hrs by Western blot analysis | Homo sapiens | 3 | ALA5104222 | cell-based format | Scientific Literature | |
16. | ALA5107751 | Binding | PROTAC activity at VHL/HDAC3 in human HCT-116 cells assessed as induction of HDAC3 degradation by measuring maximum efficacy at 10 uM incubated for 24 hrs by Western blot analysis relative to control | Homo sapiens | 2 | ALA5104222 | cell-based format | Scientific Literature | |
17. | ALA5107772 | Binding | PROTAC activity at VHL/HDAC3 in human HCT-116 cells assessed as HDAC3 level at 0.01 uM incubated for 24 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA5104222 | cell-based format | Scientific Literature | |
18. | ALA5107773 | Binding | PROTAC activity at VHL/HDAC3 in human HCT-116 cells assessed as HDAC3 level at 0.025 uM incubated for 24 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA5104222 | cell-based format | Scientific Literature | |
19. | ALA5107774 | Binding | PROTAC activity at VHL/HDAC3 in human HCT-116 cells assessed as HDAC3 level at 0.05 uM incubated for 24 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA5104222 | cell-based format | Scientific Literature | |
20. | ALA5107775 | Binding | PROTAC activity at VHL/HDAC3 in human HCT-116 cells assessed as HDAC3 level at 0.1 uM incubated for 24 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA5104222 | cell-based format | Scientific Literature |