| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4605889 | B | Protac activity at VHL/HDAC1 in human MM1S cells assessed as HDAC1 degradation at 100 nM after 4 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA5045984 | B | Protac activity at VHL/HDAC1 in human HCT-116 cells assessed as induction of HDAC1 degradation at 10 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 3. | ALA5045987 | B | Protac activity at VHL/HDAC1 in human HCT-116 cells assessed as induction of HDAC1 degradation at 1 to 10 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 4. | ALA5045990 | B | Protac activity at VHL/HDAC1 in human HCT-116 cells assessed as induction of HDAC1 degradation at 1 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA5045993 | B | Protac activity at VHL/HDAC1 in human HCT-116 cells assessed as induction of HDAC1 degradation at 1 uM incubated for 24 hrs by Western blot analysis relative to control | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 6. | ALA5045996 | B | Protac activity at VHL/HDAC1 in human HCT-116 cells assessed as induction of HDAC1 degradation incubated for 24 hrs by Western blot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 7. | ALA5046000 | B | Protac activity at VHL/HDAC1 in human HCT-116 cells assessed as increase in H3K56ac levels at 10 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
| 8. | ALA5046003 | B | Protac activity at VHL/HDAC1 in human HCT-116 cells assessed as fold increase in H3K56ac at 10 uM measured after 8 hrs by Western blot analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA5046004 | B | Protac activity at VHL/HDAC1 in human HCT-116 cells assessed as induction of HDAC1 degradation at 10 uM measured after 4 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA5046006 | B | Protac activity at VHL/HDAC1 in human HCT-116 cells assessed as induction of HDAC1 degradation at 1 uM measured upto 48 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA5046009 | B | Protac activity at VHL/HDAC1 in human HCT-116 cells assessed as induction of HDAC1 degradation at 10 uM measured upto 48 hrs by Western blot analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA5046015 | B | Protac activity at VHL/HDAC1 in human HCT-116 cells assessed as reduction in LSD1 level measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA5046016 | B | Protac activity at VHL/HDAC1 in human HCT-116 cells assessed as reduction in LSD1 level measured after 48 hrs by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 14. | ALA5046017 | B | Protac activity at VHL/HDAC1 in human HCT-116 cells assessed as reduction in SIN3A level at 10 uM measured after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 15. | ALA5046029 | B | Protac activity at VHL/HDAC1 in human HCT-116 cells assessed as reduction in SIN3A level at 10 uM measured after 48 hrs by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 16. | ALA5107734 | B | PROTAC activity at VHL/HDAC1 in human HCT-116 cells assessed as induction of HDAC1 degradation at 10 uM incubated for 24 hrs by Western blot analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA5107736 | B | PROTAC activity at VHL/HDAC1 in human HCT-116 cells assessed as induction of HDAC1 degradation at 0.1 to 10 uM incubated for 24 hrs by Western blot analysis relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 18. | ALA5107742 | B | PROTAC activity at VHL/HDAC1 in human HCT-116 cells assessed as induction of HDAC1 degradation incubated for 24 hrs by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 19. | ALA5107749 | B | PROTAC activity at VHL/HDAC1 in human HCT-116 cells assessed as induction of HDAC1 degradation by measuring maximum efficacy at 10 uM incubated for 24 hrs by Western blot analysis relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 20. | ALA5107752 | B | PROTAC activity at VHL/HDAC1 in human HCT-116 cells assessed as HDAC1 level at 2.5 uM incubated for 24 hrs by Western blot analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature |
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