# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4605892 | B | Protac activity at VHL/HDAC4 in human MM1S cells assessed as HDAC4 degradation at 100 nM after 4 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
2. | ALA5130704 | B | Protac activity at VHL/HDAC4 in human Jurkat E6.1 cells assessed as induction of HDAC4 degradation incubated for 24 hrs by ELISA-based MSD electrochemiluminescence assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
3. | ALA5130705 | B | Protac activity at VHL/HDAC4 in human Jurkat E6.1 cells assessed as induction of HDAC4 degradation by measuring maximum degradation at 10 uM incubated for 24 hrs by ELISA-based MSD electrochemiluminescence assay relative to control | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
4. | ALA5130706 | B | Protac activity at VHL/HDAC4 in human Jurkat E6.1 cells assessed as induction of HDAC4 degradation at 10 uM incubated for 24 hrs by immunoblotting analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
5. | ALA5130707 | B | Protac activity at VHL/HDAC4 in human Jurkat E6.1 cells assessed as induction of HDAC4 degradation incubated for 24 hrs by immunoblotting analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
6. | ALA5130708 | B | Protac activity at VHL/HDAC4 in human Jurkat E6.1 cells assessed as induction of HDAC4 degradation at 1 uM incubated for 6 hrs in presence of proteasome inhibitor MG132 by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
7. | ALA5130709 | B | Protac activity at VHL/HDAC4 in human Jurkat E6.1 cells assessed as induction of HDAC4 degradation at 1 uM incubated for 6 hrs in presence of proteasome inhibitor carfilzomib by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
8. | ALA5130710 | B | Protac activity at VHL/HDAC4 in human Jurkat E6.1 cells assessed as induction of HDAC4 degradation at 100 nM incubated for 6 hrs in presence of proteasome inhibitor MG132 by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
9. | ALA5130711 | B | Protac activity at VHL/HDAC4 in human Jurkat E6.1 cells assessed as induction of HDAC4 degradation at 100 nM incubated for 6 hrs in presence of proteasome inhibitor carfilzomib by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
10. | ALA5130721 | B | Protac activity at VHL/HDAC4 in human Jurkat E6.1 cells assessed as induction of HDAC4 degradation incubated for 24 hrs in absence of elacridar by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
11. | ALA5130722 | B | Protac activity at VHL/HDAC4 in human Jurkat E6.1 cells assessed as induction of HDAC4 degradation preincubated with elacridar for 1 hr followed by compound addition and measured after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
12. | ALA5130734 | B | Protac activity at VHL/HDAC4 in human Jurkat E6.1 cells assessed as induction of HDAC4 degradation at 1 uM incubated for 6 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |