| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4136019 | A | Cytotoxicity against human SW620/AD300 cells by MTT assay | Homo sapiens | 31 | ALA4130548 | cell-based format | Scientific Literature | |
| 2. | ALA4136021 | A | Cytotoxicity against human SW620/AD300 cells assessed as survival rate at 2 uM by MTT assay relative to control | Homo sapiens | 31 | ALA4130548 | cell-based format | Scientific Literature | |
| 3. | ALA4136029 | F | Downregulation of ABCB1 protein expression in human SW620/AD300 cells at 1 to 4 uM after 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA4130548 | cell-based format | Scientific Literature | |
| 4. | ALA4136030 | F | Downregulation of ABCB1 protein expression in human SW620/AD300 cells at 2 uM after 48 hrs by Hoechst 33258 staining based immunofluorescence assay | Homo sapiens | 1 | ALA4130548 | cell-based format | Scientific Literature | |
| 5. | ALA4136031 | F | Effect on subcellular distribution of ABCB1 in human SW620/AD300 cells at 2 uM after 48 hrs by Hoechst 33258 staining based immunofluorescence assay | Homo sapiens | 1 | ALA4130548 | cell-based format | Scientific Literature | |
| 6. | ALA4145371 | A | Cytotoxicity against human SW620/AD300 cells assessed as survival at 2 uM after 72 hrs by MTT assay relative to control | Homo sapiens | 60 | ALA4138318 | cell-based format | Scientific Literature | |
| 7. | ALA4145375 | F | Effect on ABCB1 expression in human SW620/AD300 cells up to 4 uM after 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA4138318 | cell-based format | Scientific Literature | |
| 8. | ALA4145376 | F | Effect on subcellular localization of ABCB1 in human SW620/AD300 cells at 2 uM after 48 hrs by Hoechst 33258 staining-based immunofluorescence assay | Homo sapiens | 3 | ALA4138318 | cell-based format | Scientific Literature | |
| 9. | ALA4145399 | F | Antitumor activity against ABCB1 overexpressing human SW620/AD300 cells xenografted in BALB/c nude mouse assessed as reduction in tumor volume at 20 mg/kg/day, po measured after 21 days | Homo sapiens | 1 | ALA4138318 | organism-based format | Scientific Literature | |
| 10. | ALA4145400 | F | Antitumor activity against ABCB1 overexpressing human SW620/AD300 cells xenografted in BALB/c nude mouse assessed as reduction in tumor volume at 5 mg/kg/3 day, ip measured after 21 days | Homo sapiens | 1 | ALA4138318 | organism-based format | Scientific Literature | |
| 11. | ALA4145401 | F | Antitumor activity against ABCB1 overexpressing human SW620/AD300 cells xenografted in BALB/c nude mouse assessed as reduction in tumor volume at 20 mg/kg/day, po cotreated with 5 mg/kg, ip paclitaxel measured after 21 days | Homo sapiens | 1 | ALA4138318 | organism-based format | Scientific Literature | |
| 12. | ALA4157631 | A | Cytotoxicity against human SW620/AD300 cells assessed as decrease in cell survival after 72 hrs by MTT assay | Homo sapiens | 1 | ALA4152352 | cell-based format | Scientific Literature | |
| 13. | ALA4157713 | F | Effect on expression of ABCB1 protein in human SW620/Ad300 cells at 10 to 20 uM by Western blot method | Homo sapiens | 1 | ALA4152352 | cell-based format | Scientific Literature | |
| 14. | ALA4157714 | F | Effect on expression of ABCB1 protein in human SW620/Ad300 cells at 20 uM after 24 to 96 hrs by Western blot method | Homo sapiens | 1 | ALA4152352 | cell-based format | Scientific Literature | |
| 15. | ALA4198055 | F | Cytotoxicity against human SW620/AD300 cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 8 | ALA4196060 | cell-based format | Scientific Literature | |
| 16. | ALA4265272 | A | Cytotoxicity against human SW620/AD300 cells after 72 hrs by MTT assay | Homo sapiens | 1 | ALA4261637 | cell-based format | Scientific Literature | |
| 17. | ALA4265315 | F | Effect on ABCB1 expression in human SW620/AD300 cells at 20 uM up to 96 hrs by Western blot analysis | Homo sapiens | 1 | ALA4261637 | cell-based format | Scientific Literature | |
| 18. | ALA4265316 | F | Effect on ABCB1 expression in human SW620/AD300 cells at 10 to 20 uM by Western blot analysis | Homo sapiens | 1 | ALA4261637 | cell-based format | Scientific Literature | |
| 19. | ALA4265317 | F | Effect on subcellular localization of ABCB1 in human SW620/AD300 cells at 10 to 20 uM after 72 hrs by Hoechst 33342 staining-based immunofluorescence assay | Homo sapiens | 1 | ALA4261637 | cell-based format | Scientific Literature | |
| 20. | ALA4604501 | F | Antiproliferative activity against human SW620/AD300 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 2 | ALA4602664 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!