| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1033803 | F | Induction of apoptosis in human T98 cells expressing mutant p53 protein assessed as cell membrane morphological changes at 100 uM after 48 hrs by phase contrast microscopy | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA1033805 | F | Induction of apoptosis in human T98 cells expressing mutant p53 protein assessed as DNA fragmentation at 100 uM after 48 hrs using DAPI staining by UV/fluorescence microscopy | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA3784814 | F | Induction of apoptosis in human T98 cells assessed as late apoptotic cells at 100 uM after 24 hrs by Annexin-V-FITC/propidium iodide staining based flow cytometry analysis (Rvb = 2.7 +/- 1.4 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA3784815 | F | Induction of apoptosis in human T98 cells assessed as early apoptotic cells at 100 uM after 24 hrs by Annexin-V-FITC/propidium iodide staining based flow cytometry analysis (Rvb = 1.1 +/- 0.3 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA3784816 | F | Induction of apoptosis in human T98 cells assessed as alive cells at 100 uM after 24 hrs by Annexin-V-FITC/propidium iodide staining based flow cytometry analysis (Rvb = 95 +/- 5.6 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA3784818 | F | Induction of apoptosis in human T98 cells assessed as late apoptotic cells at 50 uM after 24 hrs by Annexin-V-FITC/propidium iodide staining based flow cytometry analysis (Rvb = 2.7 +/- 1.4 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA3784819 | F | Induction of apoptosis in human T98 cells assessed as early apoptotic cells at 50 uM after 24 hrs by Annexin-V-FITC/propidium iodide staining based flow cytometry analysis (Rvb = 1.1 +/- 0.3 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA3784820 | F | Induction of apoptosis in human T98 cells assessed as alive cells at 50 uM after 24 hrs by Annexin-V-FITC/propidium iodide staining based flow cytometry analysis (Rvb = 95 +/- 5.6 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA3784823 | F | Effect on caspase 3 mRNA expression levels in human T98 cells at 50 to 100 uM by real-time PCR assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA3784824 | F | Effect on caspase 8 mRNA expression levels in human T98 cells at 50 to 100 uM by real-time PCR assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA3784825 | F | Effect on caspase 9 mRNA expression levels in human T98 cells at 50 to 100 uM by real-time PCR assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA3784826 | F | Effect on cytochrome-c mRNA expression levels in human T98 cells at 50 to 100 uM by real-time PCR assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4610641 | F | Antiproliferative activity against human T98 cells assessed as reduction in cell viability at 3 to 300 uM incubated for 5 days by Prestoblue reagent based assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 14. | ALA4610642 | F | Antiproliferative activity against human T98 cells assessed as reduction in cell viability incubated for 5 days by Prestoblue reagent based assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 15. | ALA4610646 | F | Antiproliferative activity against human T98 cells assessed as reduction in cell viability at 1 to 1000 nM incubated for 5 days by Prestoblue reagent based assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 16. | ALA4610647 | F | Synergistic antiproliferative activity against human T98 cells assessed as reduction in cell viability at 10 to 1000 nM in presence of GDC0941 incubated for 5 days by Prestoblue reagent based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4610652 | F | Antiproliferative activity against human T98 cells assessed as reduction in cell viability at 1 to 30000 nM incubated for 5 days by Prestoblue reagent based assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 18. | ALA4610653 | F | Synergistic antiproliferative activity against human T98 cells assessed as reduction in cell viability at 100 nM in presence of GDC0941 incubated for 5 days by Prestoblue reagent based assay | Homo sapiens | 1 | cell-based format | Scientific Literature |
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