| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4354713 | A | Cytotoxicity against human S1 cells assessed as inhibition of cell viability at 5 to 25 uM incubated for 2 hrs by MTT assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA4629389 | F | Induction of apoptosis in human S1 cells assessed as necrotic cells at 10 uM incubated for 48 hrs in presence of topotecan by annexin V/propidium iodide staining based flow cytometry (Rvb = 0.2%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4629390 | F | Induction of apoptosis in human S1 cells assessed as late apoptotic cells at 10 uM incubated for 48 hrs in presence of topotecan by annexin V/propidium iodide staining based flow cytometry (Rvb = 3.6%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4629391 | F | Induction of apoptosis in human S1 cells assessed as early apoptotic cells at 10 uM incubated for 48 hrs in presence of topotecan by annexin V/propidium iodide staining based flow cytometry (Rvb = 2%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4629392 | F | Induction of apoptosis in human S1 cells assessed as viable cells at 10 uM incubated for 48 hrs in presence of topotecan by annexin V/propidium iodide staining based flow cytometry (Rvb = 94.1%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4629393 | F | Induction of apoptosis in human S1 cells assessed as necrotic cells at 5 uM incubated for 48 hrs by annexin V/propidium iodide staining based flow cytometry (Rvb = 0.2%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4629394 | F | Induction of apoptosis in human S1 cells assessed as late apoptotic cells at 5 uM incubated for 48 hrs by annexin V/propidium iodide staining based flow cytometry (Rvb = 3.6%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4629395 | F | Induction of apoptosis in human S1 cells assessed as early apoptotic cells at 5 uM incubated for 48 hrs by annexin V/propidium iodide staining based flow cytometry (Rvb = 2%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4629396 | F | Induction of apoptosis in human S1 cells assessed as viable cells at 5 uM incubated for 48 hrs by annexin V/propidium iodide staining based flow cytometry (Rvb = 94.1%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4629397 | F | Induction of apoptosis in human S1 cells assessed as necrotic cells at 10 uM incubated for 48 hrs by annexin V/propidium iodide staining based flow cytometry (Rvb = 0.2%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4629398 | F | Induction of apoptosis in human S1 cells assessed as late apoptotic cells at 10 uM incubated for 48 hrs by annexin V/propidium iodide staining based flow cytometry (Rvb = 3.6%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4629399 | F | Induction of apoptosis in human S1 cells assessed as early apoptotic cells at 10 uM incubated for 48 hrs by annexin V/propidium iodide staining based flow cytometry (Rvb = 2%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4629401 | F | Induction of apoptosis in human S1 cells assessed as viable cells at 10 uM incubated for 48 hrs by annexin V/propidium iodide staining based flow cytometry (Rvb = 94.1%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4629408 | F | Induction of pheophorbide A accumulation in human S1 cells at 20 uM incubated for 1 hr by FACScan flow cytometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4629422 | F | Cytotoxicity against human S1 cells after 72 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4629464 | F | Effect on topotecan-induced cytotoxicity against human S1 cells assessed as fold change in topotecan IC50 at 3 uM after 72 hrs by MTT assay relative to topotecan IC50 | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4629465 | F | Effect on topotecan-induced cytotoxicity against human S1 cells assessed as fold change in topotecan IC50 at 2 uM after 72 hrs by MTT assay relative to topotecan IC50 | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4629466 | F | Effect on topotecan-induced cytotoxicity against human S1 cells assessed as fold change in topotecan IC50 at 1 uM after 72 hrs by MTT assay relative to topotecan IC50 | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 19. | ALA4629467 | F | Effect on topotecan-induced cytotoxicity against human S1 cells assessed as fold change in topotecan IC50 at 0.5 uM after 72 hrs by MTT assay relative to topotecan IC50 | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4629468 | F | Effect on topotecan-induced cytotoxicity against human S1 cells by measuring topotecan IC50 at 3 uM after 72 hrs by CCK8 assay (Rvb = 9.21 +/- 1.45 nM) | Homo sapiens | 1 | cell-based format | Scientific Literature |
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