# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4617297 | B | Inhibition of SREBP (unknown origin) expressed in HEK293 cells assessed as reduction in LDLr promotor activity after 24 hrs by luciferase reporter assay | Homo sapiens | 13 | ALA4616603 | cell-based format | Scientific Literature | |
2. | ALA4824174 | B | Inhibition of SREBP (unknown origin) expressed in CHO-K1 cells at 5 uM by luciferase reporter assay | Homo sapiens | 28 | ALA4823262 | cell-based format | Scientific Literature | |
3. | ALA4824182 | B | Inhibition of SREBP (unknown origin) expressed in CHO-K1 cells by luciferase reporter assay | Homo sapiens | 6 | ALA4823262 | cell-based format | Scientific Literature | |
4. | ALA4824184 | B | Inhibition of SREBP (unknown origin) expressed in CHO-K1 cells assessed as reduction in precursor SREBP protein level at 5 uM after 24 hrs by Western blotting analysis | Homo sapiens | 2 | ALA4823262 | cell-based format | Scientific Literature | |
5. | ALA4824185 | B | Inhibition of SREBP (unknown origin) expressed in CHO-K1 cells assessed as reduction in mature SREBP protein level at 5 uM after 24 hrs by Western blotting analysis | Homo sapiens | 2 | ALA4823262 | cell-based format | Scientific Literature | |
6. | ALA4824187 | B | Inhibition of SREBP (unknown origin) expressed in CHO-K1 cells assessed as reduction in precursor SREBP protein level at 1 uM after 24 hrs by Western blotting analysis | Homo sapiens | 1 | ALA4823262 | cell-based format | Scientific Literature | |
7. | ALA4824188 | B | Inhibition of SREBP (unknown origin) expressed in CHO-K1 cells assessed as reduction in mature SREBP protein level at 1 uM after 24 hrs by Western blotting analysis | Homo sapiens | 1 | ALA4823262 | cell-based format | Scientific Literature | |
8. | ALA4838296 | B | Induction of SREBP degradation in human HepG2 cells at 10 uM preincubated with cycloheximide for 1 hr followed by compound additon by Western blot analysis | Homo sapiens | 1 | ALA4837214 | cell-based format | Scientific Literature | |
9. | ALA4838308 | B | Induction of SREBP degradation in human HepG2 cells at 10 uM preincubated with MG-132 for 1 hr followed by compound additon and measured after 4 hrs by Western blot analysis | Homo sapiens | 1 | ALA4837214 | cell-based format | Scientific Literature | |
10. | ALA4838309 | B | Induction of SREBP degradation expressed in human HEK293T cells assessed as increase in SREBP ubiquitination at 10 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4837214 | cell-based format | Scientific Literature |