| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4618906 | B | Binding affinity to full length human N-terminal His-tagged/GST-tagged Naa50 expressed in Escherichia coli BL21(DE3) cells assessed as change in melting temperature at 250 uM after 15 mins in presence of acetyl-CoA by SYPRO Orange dye based DSF assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA4618907 | B | Binding affinity to full length human N-terminal His-tagged/GST-tagged Naa50 expressed in Escherichia coli BL21(DE3) cells assessed as change in melting temperature at 250 uM after 15 mins in absence of acetyl-CoA by SYPRO Orange dye based DSF assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 3. | ALA4618908 | B | Binding affinity to full length human N-terminal His-tagged/GST-tagged Naa50 expressed in Escherichia coli BL21(DE3) cells in presence of CoA by SPR analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA4618909 | B | Inhibition of wild type human Naa50 (1852 to 2082 residues) expressed in Escherichia coli BL21(DE3) cells using MLGPEGGEGK peptide as substrate after 75 mins in presence of acetyl CoA by rapidfire mass spectrometry analysis | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
| 5. | ALA4618910 | B | Binding affinity to full length human N-terminal His-tagged/GST-tagged Naa50 expressed in Escherichia coli BL21(DE3) cells in presence of acetyl CoA by SPR analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 6. | ALA4618911 | B | Binding affinity to Naa50 in human A549 cell lysates assessed as thermal stabilization of protein at 50 uM after 30 mins followed by heating at 40 to 64 degC for 3 mins by immunoblot-based CESTA | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4618914 | B | Binding affinity to Naa50 in human A549 cell lysates assessed as thermal stabilization of protein at 50 uM after 30 mins followed by heating at 55 degC for 3 mins by immunoblot-based CESTA | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4618915 | B | Inhibition of Naa50 in human HeLa cells up to 50 uM after 1 hr in presence of Lys-CoA sepharose resin by Lys-CoA sepharose resin based Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4618916 | B | Binding affinity to full length human N-terminal His-tagged/GST-tagged Naa50 expressed in Escherichia coli BL21(DE3) cells assessed as association rate constant by SPR analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA4618917 | B | Binding affinity to full length human N-terminal His-tagged/GST-tagged Naa50 expressed in Escherichia coli BL21(DE3) cells assessed as association rate constant in presence of acetyl-CoA by SPR analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 11. | ALA4618918 | B | Binding affinity to full length human N-terminal His-tagged/GST-tagged Naa50 expressed in Escherichia coli BL21(DE3) cells assessed as association rate constant by SPR analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 12. | ALA4618919 | B | Binding affinity to full length human N-terminal His-tagged/GST-tagged Naa50 expressed in Escherichia coli BL21(DE3) cells assessed as dissociation rate constant in presence of acetyl-CoA by SPR analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 13. | ALA4618920 | B | Binding affinity to full length human N-terminal His-tagged/GST-tagged Naa50 expressed in Escherichia coli BL21(DE3) cells assessed as half life for dissociation by SPR analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 14. | ALA4618921 | B | Binding affinity to full length human N-terminal His-tagged/GST-tagged Naa50 expressed in Escherichia coli BL21(DE3) cells assessed as half life for dissociation in presence of acetyl-CoA by SPR analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 15. | ALA4618922 | B | Binding affinity to full length human N-terminal His-tagged/GST-tagged Naa50 expressed in Escherichia coli BL21(DE3) cells in by SPR analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 16. | ALA5034367 | B | Inhibition of human NatE using AcCoA and H4 peptide as substrate at 10 uM incubated for 12 min at room temperature | Homo sapiens | 2 | single protein format | Scientific Literature |
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